汪义和,张燕琴,刘如星,邵芯仪,刘宝根.检测唾液IgM抗-HAV诊断甲型肝炎的研究[J].Chinese journal of Epidemiology,1992,13(1):9-11 |
检测唾液IgM抗-HAV诊断甲型肝炎的研究 |
Study on Diagnosis of Hepatitis A by Testing Salivary IgM Anti-HAV |
Received:November 22, 1990 Revised:March 05, 1991 |
DOI: |
KeyWord: 唾液诊断 IgM抗-HAV 甲型病毒性肝炎 |
English Key Word: Salivary diagnosis IgM anti-HAV Hepatitis A |
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Abstract: |
本文采用检测唾液IgM抗-HAV来诊断甲型病毒性肝炎(甲肝)进行了研究。结果表明,IgM抗-HAV能可靠地在血清学证实的58例急性甲肝和9例甲乙混合感染的患者唾液中检出,而不能在非甲肝患者其中包括84例急性乙肝和30例非甲非乙肝及10例健康人唾液中检出。证明采用唾液标本来诊断甲肝是特异的。唾液比血清更易获得,这就为今后甲肝的诊断和流行病学调查提供了更有利的条件。 |
English Abstract: |
The use of salivary samples to diagnose acute hepatitis A was investigated. Result indicated that IgM anti-HAV can be reliably detected in saliva of 58 cases with acute hepatitis A and 9 cases with mixed infection of hepatitis A and B. It is not present in soliva of individuals without recent hepatitis A including 84 cases with acute hepatitis B, 30 cases of hepatitis non A non B and 10 healthy individuals. It was suggested that use of salivary samples to diagnose hepatitis A was specific. It's concluded that saliva is a convenient and satisfactory alternative to serum for the clinical diagnosis and epidemiological investigation of hepatitis A infection. |
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