| 赵仲堂,郝凤荣,潘玉珍,古钦民,展雅琴,石素英,娄惠生,王淑珍.孕妇弓形体感染与异常妊娠结局关系的前瞻性研究[J].Chinese journal of Epidemiology,1992,13(3):154-157 |
| 孕妇弓形体感染与异常妊娠结局关系的前瞻性研究 |
| A Prospective Study on the Relationship Between Abnormal Pregnant Outcome and Toxoplasma Gondii Infection |
| Received:June 01, 1990 Revised:June 25, 1990 |
| DOI： |
| KeyWord: 前瞻性研究 孕妇 弓形体感染 异常妊娠结局 |
| English Key Word: Prospective study Pregnant women Toxoplasma gondii infection Abnormal Pregnant outcome |
| FundProject:本项研究是由中华人民共和国卫生部青年科学研究基金资助 |
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| Abstract: |
| 对2 821名孕妇按弓形体感染情况分为三组,随访妊娠结局。结果发现,自然流产、早产、死胎和先天缺陷的总发生率分别为0.67%、3.47%、0.85%和0.96%。新近感染或活动性感染组这四种异常妊娠结局的发生率均显著高于未受感染组,相对危险度估计值(ORmh)分别为7.38、3.52,8.68和9.44。过去感染组与未受感染组异常妊娠结局的发生率差异均无统计学意义。抗体检出时间与异常妊娠结局发生的关系分析提示,先天缺陷的发生与孕三个月内感染有关。 |
| English Abstract: |
2821 pregnant women were divided into three groups according to the phenomena of Toxoplasma gondii infection, and the pregnancy outcomes were followed up.
Results show that the total incidence rates of spontaneous abortion, premature birth, still birth and congenital defects are 0.67%, 3.47%, 0.85% and 0.96% respectively.These four rates in the group serodiagnosed as recently or actively infected are significantly higher than that diagnosed as no evidence of infection 8 and the relative risk estimates (ORmh) are 7.38, 3.52, 8.68 and 9.44 respectively. Differences of the four rates between group diagnosed as past infection and that of no evidence of infection are not statistically significant. Analysis between the time of serodiagnosis and the incidence of abnormal pregnant outcome shows that congenital defects is statistically related with infection in the first trimester of gestation. |
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