| 吴在川,蒋豫图,张习坦,陈万荣,阎惠萍,汪爱勤,王志明,田埼琦.乙型肝炎X抗原和抗-HBx的血清流行病学调查[J].Chinese journal of Epidemiology,1992,13(4):205-207 |
| 乙型肝炎X抗原和抗-HBx的血清流行病学调查 |
| Seroepidemiological Study of Hepatitis B Virus X Antigen (HBxAg) and Anti-HBx Antibodies in Patients with Hepatitis B |
| Received:October 26, 1991 Revised:January 21, 1992 |
| DOI： |
| KeyWord: 乙型肝炎X抗原 抗体 血清流行病学 |
| English Key Word: Hepatitis B virus X antigen Antibody Seroepidemiology |
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| Abstract: |
| 对437例乙型肝炎和肝癌病人进行了HBxAg和抗-HBx的血清流行病学调查。结果表明HBxAg阳性率为3.66%(16/437),抗-HBx阳性率为2.97%(13/437);HBxAg主要出现在HBsAg、HBeAg和抗-HBc阳性,而抗-HBe为阴性的血清中,它与抗-HBs的关系不密切;抗-HBx主要出现在HBeAg和抗-HBc阳性,而HBsAg和抗-HBe为阴性的血清中,它与抗-HBs的关系亦不密切。上述结果说明HBxAg/抗-HBx系统的出现与体内乙型肝炎的病毒复制有关,同时也说明抗-HBx不是保护性抗体。 |
| English Abstract: |
| A total of 437 patients with hepatitis B were tested for serum HBxAg and auti-HBx in a seroepidemiological study. It was shown that the HBxAg positivity rate was 3.66%(16/437), the anti-HBx positivity rate was 2.97% (13/437). HBxAg was most frequently present in HBsAg, HBeAg, and anti-HBc positive, but anti-HBe negative sera. AntiHBx was most frequently present in HBeAg and anti-HBc positive, but HBsAg and antiHBe negative sera. Both the presence of HBxAg and anti-HBx antibodies showed no significant relationship with the presence of serum antiHBs antibodies. These results indicated that serum HBxAg/anti-HBx system was related to the replications of HBV in the HBV infected human body, and anti-HBx were not protective antibody. |
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