| 刘云嵘,邱淑华,吴裕浩,陈学煌,黄真嘉,徐铎,蔡光宗,张立英,狄志义,张桂英,王定家,叶鑫生,王学梅,孙林,杨书章.输卵管注药绝育术有效性及安全性的前瞻性流行病学研究[J].Chinese journal of Epidemiology,1992,13(4):221-225 |
| 输卵管注药绝育术有效性及安全性的前瞻性流行病学研究 |
| Prospective Epidemiological Study on the Efficacy and Safety of Female Tubal Sterilization by Chemical Instillation |
| Received:March 21, 1991 Revised:May 06, 1991 |
| DOI： |
| KeyWord: 输卵管注药绝育 前瞻性队列研究 |
| English Key Word: Tubal sterilization Prospective epidemiological study |
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| Abstract: |
| 本文为一项输卵管注药绝育术的前瞻性队列研究。队列1使用显影苯酚胶浆共834例,队列2使用8%阿的平苯酚糊剂871例。二年随访率98.5%。生命表法分析,第24个顺序月每100名妇女的累积成功率两队列分别为91.9%和97.4%。其间有显著性差别。绝育效果主要取决于输卵管注药后X光显影的充盈长度。多元判别分析也显示同样的结论。所有研究对象在术中和术后未见严重并发症。术后发烧,队列2 (8%)高于队列1(4.4%)。本术对月经无明显影响。研究结果表明该术是一种简便、安全、有效的女性绝育术。 |
| English Abstract: |
| This is a prospective study on clinical efficacy and safety of female sterilization by chemical agents.A total number of 1705 subjects were randomly divided into two groups. Phenol mucilage (PM) was used in group 1 (834 cases) and phenol-atabrine paste (PAP) was used in group 2 (871 cases).All the characteristics of the subjects were proportionate and comparable to two groups.The follow-up rate was 98.5% at the end of 2 years. Using life table analysis, the results show that the cumulative success rate per 100 women of two groups using PAP and PM was 97 and 91.1%respectively.There was significant difference between the two groups.The efficacy of the methods was related with the developed length of roentgenographic shadow after instillation. Multiple discriminatory analysis showed the same results as above.There was no severe complication in all cases.The post-instillation fever rate was 8% in group PAP and 4.4% in group PM, respectively.Our results indicate that female sterilization with the use of chemical agents mentioned is a simple, safe and reliable method in preventing pregnancy. |
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