| 官亚宜,王瑞芳,叶志雄,易元川,朱桂宝.幽门螺旋菌与慢性胃炎及消化性溃疡关系的配比病例对照与序贯分析研究[J].Chinese journal of Epidemiology,1993,14(2):75-77 |
| 幽门螺旋菌与慢性胃炎及消化性溃疡关系的配比病例对照与序贯分析研究 |
| A Study on the Relationship Between Helicobacter pylori and Chronic Gastritis and Peptic Ulcer by the Case-Control Method and Sequential Analysis |
| Received:March 21, 1991 Revised:February 09, 1992 |
| DOI： |
| KeyWord: 螺旋菌 胃炎 消化性溃疡 对比研究 |
| English Key Word: Helicobacter Gastritis Peptic ulcer Comparative study |
| FundProject: |
| Author Name | Affiliation | | Guan Yayi | Department of Epidemiology, Tongji Medical University, Wuhan 430030 | | 王瑞芳 | Department of Epidemiology, Tongji Medical University, Wuhan 430030 | | 叶志雄 | Department of Epidemiology, Tongji Medical University, Wuhan 430030 | | 易元川 | Department of Epidemiology, Tongji Medical University, Wuhan 430030 | | 朱桂宝 | Department of Epidemiology, Tongji Medical University, Wuhan 430030 |
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| Abstract: |
| 根据活检标本的组织病理变化确定病例和对照,用群组、配比病例对照及序贯分析方法研究了幽门螺旋菌与慢性胃炎和消化性溃疡的关系,发现该菌在病例中的检出率明显高于对照,χMH2=22.70,P<0.001,OR=15.63,OR的95%可信限为5.05,48.43,病例中的慢性活动性胃炎者尤甚,OR=20.92。三种研究方法得出了一致性结果,提示幽门螺旋菌可能是该病的重要病原。 |
| English Abstract: |
| The association between Helicobacter pylori and the chronic gastritis and peptic ulcer was investigated by the case-control method, 1:1 matched study and sequential analysis. The results of three methods showed that the degree of association between Helicobacter pylori and the chronic gastritis and peptic ulcer was significant (χ2=22.70, P<0.001. OR=15.63, 95% CI of OR was 5.05, 48.43), especially that between Helicobacter pylori and active chronic gastritis (OR=20.92). The results indicate that Helicobacter pylori might be an etiological factor for patients with chronic gastritis and peptic ulcer. |
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