| 孙红妹,郭章溉,吴连方,张佳杰,王丽红,李敏,曹兰华.解脲支原体与新生儿宫内感染[J].Chinese journal of Epidemiology,1993,14(2):81-83 |
| 解脲支原体与新生儿宫内感染 |
| Ureaplasma urealyticum and Intrauterine Infection of Fetus |
| Received:March 20, 1992 Revised:November 18, 1992 |
| DOI： |
| KeyWord: 解脲支原体 宫内感染 |
| English Key Word: Ureaplasm Intrauterine infection |
| FundProject:本文为国家自然科学基金资助项目 |
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| Abstract: |
| 妊娠期解脲支原体(Uu)感染可引起不良的妊娠结局,为确定新生儿能否在宫内感染Uu,我们对65例Uu血清抗体阳性孕妇的胎盘进行Uu分离,结果13例阳性。其中6例病理检查见急、慢性炎细胞浸润等改变。用ELISA法检测5例阳性胎盘胎儿脐血特异IgM,3例阳性。代谢抑制试验测出其中1例抗原血清型为T8型。从部分胎盘培养、病理改变及脐血特异抗体的一致性可见,Uu感染可发生于宫内,给早期诊断围产期Uu感染提供了新手段。 |
| English Abstract: |
| Ureaplasma urealyticum (Uu) infection in pregnancy can lead to a poor outcome. To confirm the relation between Uu and intrauterine infection, 65 placentas were taken for isolation and identification of Uu from pregnant women with positive antibody to Uu. Uu was isolated from 13 (20%) of the 65 placentas. The pathologic examination of 6 placentas showed that there were acute or chronic inflammatory cell infiltration. Cord blood IgM antibody was examined by ELISA from 5 cases in which Uu was isolated from placentas and 3 of them was positive to Uu. The 5 cord blood specimens were assayed by the metabolic inhibition test for serotypes of Uu, and one of them was serotype 8. Since the isolation of Uu from some pregnant women, the pathologic changes of placentas, and the detection of specific IgM from cord blood showed a good consistency, we conclude that the Uu infection may occur in utero. |
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