陕西地区原发性肝癌的病因流行病学研究

汪爱勤; 李远贵; 王珊珊; 陈友绩; 杨继震; 郭宇良

Abstract

汪爱勤,李远贵,王珊珊,陈友绩,杨继震,郭宇良.陕西地区原发性肝癌的病因流行病学研究[J].Chinese journal of Epidemiology,1993,14(4):208-211

陕西地区原发性肝癌的病因流行病学研究

An Epidemiologic Study on the Etiology of Primary Hepatocellular Carcinoma in Shaanxi

Received:July 31, 1992 Revised:October 04, 1992

DOI：

KeyWord: 原发性肝癌病例对照研究病因学

English Key Word: Hepatocellular carcinoma Etiology Case-control study

FundProject:

Author Name	Affiliation
Wang Aiqin	Department of Epidemiology, The 4th Military Medical University, Xi'an 710032
李远贵	Department of Epidemiology, The 4th Military Medical University, Xi'an 710032
王珊珊	Department of Epidemiology, The 4th Military Medical University, Xi'an 710032
陈友绩	Department of Epidemiology, The 4th Military Medical University, Xi'an 710032
杨继震	第四军医大学西京医院普外科
郭宇良	第四军医大学西京医院普外科

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Abstract:

本文报告了陕西地区110例原发性肝癌(PHC)的配对病例对照研究结果。结果显示HBV与PHC关系最密切。此外,社会心理因素、遗传因素、吃蔬菜和水果少均可能与PHC发生有关。并且HBV感染与遗传因素、饮食因素之间均有协同作用。提示HBV感染除可能有直接致癌作用外,还可与其它因素共同起到协同致癌作用。Logistic多因素分析结果显示HBV感染与负性事件可能是PHC的主要危险因素,蔬菜水果可能为保护因素。

English Abstract:

The result of a matched case-control study on 110 cases of primary hepatocellular carcinoma (PHC) in Shaanxi is reported. It was shown that HBV was closely associaled with PHC. Besides, psychosocial and genetics factors could be risk factors. Vegetables and fruits might be protective factors. Synergistic action between HBV and inheritance and foods was observed.Logistic regression analysis showed that HBV infection and negative events were possibly the risk factors, while vegetables and fruits were probably the protective factors.

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