| 唐时幸,马贤凯,张习坦,蒋豫图.我国部分地区献血员HCV感染的血清流行病学研究[J].Chinese journal of Epidemiology,1993,14(5):271-274 |
| 我国部分地区献血员HCV感染的血清流行病学研究 |
| Seroepidemiological Study on Hepatitis C Virus Infection among Blood Donors from Various Regions in China |
| Received:August 02, 1992 Revised:November 23, 1992 |
| DOI： |
| KeyWord: 丙型肝炎病毒 丙型肝炎病毒抗体 供血员 血清流行病学 |
| English Key Word: Hepatitis C virus Anti-HCV antibody Blood donors Seroepidemiology |
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| Abstract: |
| 对我国部分地区献血员共2273人HCV感染的血清流行病学进行了研究。义务献血员抗—HCV检出率为0~1.10%,辽宁和安徽职业献血员抗-HCV检出率分别为1.49%和3.14%,但河北和内蒙职业献血员抗-HCV检出率高达30.13%和31.86%。既往有肝炎病史、ALT异常史以及ALT异常者抗-HCV检出率明显高于无肝炎病史和ALT正常者;献血浆是感染HCV的主要原因;献血年限越长,献血次数越多,HCV感染率越高。不同年龄和不同性别献血员HCV感染率无显著性差异。不同地区献血员抗-HCV抗体谱有所不同。 |
| English Abstract: |
| A total of 2273 blood donors from various regions in China were tested for serum anti-HCV antibodies in a seroepidemiological study. The prevalence of anti-HCV in Volunteer blood donors was 0~1.10%, which was lower than that in professinal blood donors from Liaoning and Anhui Provinces (1.49%and 3.14%, respectively), whereas the positivity rate of anti-HCV was as high as 30.13% in the professional blood donors from Hebei Province and 31.86% in those from Inner Mongolia Autonomous Region. The prevalence of anti-HCV was significantly higher in the blood donors with history of hepatitis and abnormal ALT levels than those without hepatitis and with normal ALT. Plasma donation was the main cause of HCV infection. However, the prevalence of anti-HCV showed no significant sex and age differences even though the anti-HCV activity profile showed geographic difference. |
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