| 吴先国,罗光荣,许传梅.沙市地区某些人群抗-HCV调查[J].Chinese journal of Epidemiology,1993,14(6):331-333 |
| 沙市地区某些人群抗-HCV调查 |
| Investigation on Anti-HCV Antibody in Shashi District |
| Received:February 09, 1993 Revised:March 30, 1993 |
| DOI： |
| KeyWord: 抗-HCV |
| English Key Word: Anti-HCV antibody |
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| Abstract: |
| 用第二代抗-HCV试剂检测沙市地区2084名献血员与890名肝病患者。结果献血员抗-HCV阳性率为0.29%,肝病患者为1.35%,表明沙市地区存在HCV感染,其感染率相对较低。432名甲肝与8名急性乙肝病人未检出阳性,而443名慢性乙肝中有11例阳性,阳性率为2.48%,5例肝硬化病人中有1例阳性。提示混合或重叠HCV感染,对HBV感染的慢性化、肝硬化起一定促进作用。最后作者慎重提出试验结果的假阳性现象及其避免方法。 |
| English Abstract: |
| In Shashi District, 2084 blood donors and 890 patients with liver diseases have been tested for anti-HCV antibody by using the second generation reagent. As a result, the blood donors showed a positive rate of 0.29% and the patients with liver diseases 1.35%. This indicated that HCV virus infection was present in Shashi District, and the infection is relatively low. Positive result was not found among 432 patients with hepatitis A and 8 patients with actue hepatitis B, while 11 out of 443 patients with chronic hepatitis B showed positive result with a positive rate of 2.48%. One of five patients with active cirrhosis of liver was positive for anti-HCV antibody. It indicates that the mixed or cross HCV infection might lead to chronicity of the HCV infection and active cirrhosis. |
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