Abstract
冯方波,张薇芬,周国萍,张首印,袁玉民,吴宜恕.北京地区莱姆病的发现及临床研究[J].Chinese journal of Epidemiology,1994,15(1):10-13
北京地区莱姆病的发现及临床研究
Discovery and Clinical Investigation of Lyme Disease in Beijing Area
Received:March 24, 1993  Revised:June 04, 1993
DOI:
KeyWord: 莱姆病    伯氏—包柔氏螺旋体
English Key Word: Lyme disease  Borrelia burgdorferi  Haemaphysalis longicornis
FundProject:
Author NameAffiliation
Feng Fangpo No. 261 Hospital of PLA, Beijing 100094 
Zhang Weifen No. 261 Hospital of PLA, Beijing 100094 
Zhou Guoping No. 261 Hospital of PLA, Beijing 100094 
张首印 No. 261 Hospital of PLA, Beijing 100094 
袁玉民 No. 261 Hospital of PLA, Beijing 100094 
吴宜恕 No. 261 Hospital of PLA, Beijing 100094 
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Abstract:
      作者报道北京地区存在莱姆病感染。应用IFA法检测自然人群1314人抗BB螺旋体抗体,感染率11.87%;传播媒介为长角血蜱,应用改良BSK培养液分别从蜱、人血液中分离培养出BB螺旋体6株;取30例皮肤病变组织作病理检查,有5例查到BB螺旋体;莱姆病患者应用大剂量青霉素或头孢三嗪治疗,有效率分别为64%及88%。
English Abstract:
      The investigation of Lyme disease in Beijing area is reported for the first time. The sera of 1314 local residents were examined by indirect immunofluorescent assay. 11.9% of them were seropositive to Borrelia burgdcrferi. The principal vector was Haemapsysalis longicornis. Six strains of B.burgdorferi were isolated from ticks or patients using modified BSK medium. Spirochetes were found in 5 of 30 patients' skin biopsy samples. Penicillin or ceftriaxone was used to treat the patients, and the effective rates were 64% and 88%, respestively.
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