Abstract
吕嘉春,施侣元.饮水与白血病[J].Chinese journal of Epidemiology,1994,15(1):19-22
饮水与白血病
Drinking Water and Leukemia
Received:July 06, 1993  Revised:September 11, 1993
DOI:
KeyWord: 饮水污染  白血病  回顾性定群研究
English Key Word: Drinking water contamination  Leukemia  Retrospective cohort study
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Author NameAffiliation
Lu Jiachun Tongji Medical University, Wuhan 430030 
Shi Luyuan Tongji Medical University, Wuhan 430030 
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Abstract:
      应用回顾性定群研究方法,探讨武汉市饮用不同水源自来水与人群白血病发病的关系。研究发现,饮用东湖(D)水源自来水的人群白血病发病率明显高于饮用长江(C)、汉江(H)水源自来水的人群,RR=1.77,95% CL=1.36~2.30,P<0.01。C组、H组间差异无显著意义。进行性别、年龄分层分析、趋势检验及相关分析,结果表明人群白血病发病相对危险度与饮用水致突变作用有显著的正相关关系,与饮用水有机卤代烃污染有关。
English Abstract:
      A retrospective cohort study was conducted to investigate the relationship between drinking water contamination and risk of leukemia in human being. It was found that the leukemia incidecne rate of group D who drank the tap-water from Donghu Lake was significantly hinger than that of the groups C and H who drank the tapwater from Changjiang River and Hangjiang River, RR=1.77, 95% CL=1.36~2.30, P<0.01. But the difference between group C and group H is not significant. By using the sex-age-strata analysis, trend and correlation analysis, the results showed that there was a significant positive correlation between the RR of incidence of leukemia and tap-water mutagenicity. It was also connected with pollution of halogenated hydrocarbons in drinking water.
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