| 王苏娜,黄元成,喻植群,汪田坤,魏镜龙,郝连杰.丙型肝炎病毒家庭内感染状况的血清学调查[J].Chinese journal of Epidemiology,1994,15(1):34-37 |
| 丙型肝炎病毒家庭内感染状况的血清学调查 |
| Serological Investigation on intrafamilial Transmission of HCV Infection |
| Received:February 23, 1993 Revised:May 07, 1993 |
| DOI： |
| KeyWord: 丙型肝炎病毒 乙型肝炎病毒 家庭内传播 |
| English Key Word: Hepatitis C virus (HCV) Hepatitis B virus (HBV) Intrafamilial transmission |
| FundProject:本研究为“八五”国家医学科技攻关资助项目 |
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| Abstract: |
| 对60例抗-HCV阳性患者的家庭成员124人进行血清学检测,并收集40例乙肝患者的家庭成员83人为对照。结果丙肝组检出抗-HCV阳性的家庭成员9人,检出率7.3%。除去有供血史的抗-HCV阳性家庭成员,检出率为1.85%(2/108)。乙肝组未检出抗-HCV阳性者。在单一丙肝家庭组中,家庭成员的HBV感染率为25.33%,而在HBV/HCV重叠感染和HBV感染组的家庭成员中,HBV的感染率为40.91%,故提示,HCV的家庭内聚集性感染的危险性远低于HBV,且母子垂直传播的危险性更低于夫妻间水平传播。 |
| English Abstract: |
| To clarify the intrafamilial trasmission of HCV infection, the antibody to HCV was assayed in 124 serum samples from the family members of 60 HCV-Ab (+) index cases (group C), and compared with that from 83 family members of 40 HCV-Ab (-) index patients with hepatitis B (group B). Nine of 124, including 2 parents, 6 spouse and 1 granddaughter, were positive for anti-HCV. The prevalence of anti-HCV was 7.3% (9/124) in total, and 1.85% (2/108) in the subjects who had no history of blood donation. None of 83 was positive for anti-HCV in group B. On the other hand, the prevalence of HBV infection was 25.33% in the group of HCV infection only, and 40.91% in the group with HBV/HCV double-infection or HBV infection, It indicates that the risk of HBV intrafamilial trasmission is higher than that of HCV, and the risk of trasmission of HCV from mother to infant may be lower than that of sexual trasmission. |
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