单采浆还输血球献血员中的丙型肝炎病毒感染的调查报告

王淑萍; 丁红; 张红旗; 鲁玉周; 杨金才; 赵其凯; 耿洪海; 朱万孚

Abstract

王淑萍,丁红,张红旗,鲁玉周,杨金才,赵其凯,耿洪海,朱万孚.单采浆还输血球献血员中的丙型肝炎病毒感染的调查报告[J].Chinese journal of Epidemiology,1994,15(2):71-73

单采浆还输血球献血员中的丙型肝炎病毒感染的调查报告

Hepatitis C Virus Infection among the Plasmapheresis Donors

Received:May 07, 1993 Revised:November 29, 1993

DOI：

KeyWord: 丙型肝炎病毒单采浆献血员抗丙型肝炎病毒抗体

English Key Word: Plasmapheresis Donors Hepatitis C virus (HCV) Anti-HCV

FundProject:

Author Name	Affiliation
Wang Shuping	Zhou Kou Biologicals Institute in Henan Province, Zhou Kou 466000
Ding Hong	Zhou Kou Biologicals Institute in Henan Province, Zhou Kou 466000
Zhang Hongqi	Zhou Kou Biologicals Institute in Henan Province, Zhou Kou 466000
鲁玉周	Zhou Kou Biologicals Institute in Henan Province, Zhou Kou 466000
杨金才	河南省黄泛区血站
赵其凯	河南省周口市血站
耿洪海	Zhou Kou Biologicals Institute in Henan Province, Zhou Kou 466000
朱万孚	北京医科大学公共卫生学院

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Abstract:

对621名单采浆HBsAg阴性献血员及354名HBsAg阴性非献血者和124名单采浆HBsAg阳性献血员及124名HBsAg阳性非献血者进行调查,结果抗-HCV阳性率分别为84.22%(523/621)、0.85%(3/354)、41.94%(52/124)、1.61%(2/124),肝炎现患率分别为34.94%(217/621)、1.98%(7/354)、18.55%(23/124)、4.84%(6/124).调查结果表明,HCV的感染和丙型肝炎的流行主要发生在单采浆还输血球献血员中。提示在单采浆还输血球过程中应注意避免医源性交叉感染以及对所有献血员、输成分血和用于制备注射用制品的血浆检测抗-HCV是非常必要的。在血浆制品的制备工艺中能否将HCV全部灭活是一个十分值得重视的问题。

English Abstract:

We have made a retrospective study on 621 HBsAg negative plasma donors. 354 HBsAg negative non-blood donors, 124 HBsAg positive plasma donors and 124 HBsAg positive non-blood donors.Results showed that the respective positive rates of anti-HCV were 84.2%, 0.85%, 41.9% and 1.6%, and that the respective prevalence rates of viral hepatitis were 34.9%, 1.98%, 18.5% and 4.8%, respectively. These figures suggest that HCV infection and the epidemic of hepatitis C mostly occur among the plasma donors.

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