上海丹麦Ⅱ(D<sub>2</sub>)卡介苗菌株的免疫效果与反应

朱光辉; 陶鸿宝; 黄珍琴; 邱奕励

Abstract

朱光辉,陶鸿宝,黄珍琴,邱奕励.上海丹麦Ⅱ(D₂)卡介苗菌株的免疫效果与反应[J].Chinese journal of Epidemiology,1994,15(2):80-82

上海丹麦Ⅱ(D₂)卡介苗菌株的免疫效果与反应

The Efficacy and side Reactions in Humans Immunized with Danish Strain of Dried BCG of Shanghai

Received:July 02, 1993

DOI：

KeyWord: 卡介苗菌株接种效果热稳定

English Key Word: BCG strain Efficacy of immunization Thermostability

FundProject:

Author Name	Affiliation
Zhu Guanghui	Shanghai Institute of Biological Products, Shanghai 200052
Tao Hongbao	Shanghai Institute of Biological Products, Shanghai 200052
Huang Zhenqin	Shanghai Institute of Biological Products, Shanghai 200052
邱奕励	Shanghai Institute of Biological Products, Shanghai 200052

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Abstract:

本文介绍了上海丹麦Ⅱ(D₂)菌株保存传代适应过程,及其对小鼠免疫保护率和人体接种阳转率与接种反应的情况,并推荐PB₃₀₂PSⅡ甲₁₀种子批菌种为我国统一菌株的候选茵种。

English Abstract:

A procedure of keeping Danish BCG strain 2 is reported. The strain is cultivated in Bile potato Medium and Suton Potato Medium alternatively with inocubation periods of two weeks. Lyophilized vaccine produced by using seeds derived from this strain gives better immunogenicity and lower side reaction to new-born babies and has better thermostability in compare with vaccines derived from strains of Beijing, Brazil, CCCP, France of Hungary

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