大理州1 044名儿童7种疫苗免疫水平现状监测

王家龙; 李洁; 胡汝源; 施吉昌; 杨武贤

Abstract

王家龙,李洁,胡汝源,施吉昌,杨武贤.大理州1 044名儿童7种疫苗免疫水平现状监测[J].Chinese journal of Epidemiology,1994,15(3):150-153

大理州1 044名儿童7种疫苗免疫水平现状监测

The Surveillance on the Present Situation of Immune Levels of 1044 Children Vaccinated with Seven Kinds of Vaccines in Dali Prefecture

Received:February 24, 1993 Revised:April 02, 1993

DOI：

KeyWord: 抗体水平监测免疫屏障

English Key Word: Antibody level Surveillance Immunelevel

FundProject:

Author Name	Affiliation
Wang jialong	Dali Prefecture Hygiene and Epidemic Prevention Station, Yunnan Province 671000
李洁	Dali Prefecture Hygiene and Epidemic Prevention Station, Yunnan Province 671000
胡汝源	Dali Prefecture Hygiene and Epidemic Prevention Station, Yunnan Province 671000
施吉昌	Dali Prefecture Hygiene and Epidemic Prevention Station, Yunnan Province 671000
杨武贤	Dali Prefecture Hygiene and Epidemic Prevention Station, Yunnan Province 671000

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Abstract:

1991年分层随机抽取12个县(市)的4、8、12岁组儿童1044名,按卫生部《计划免疫技术管理规程》对7种疫苗的免疫现状进行了监测。结果:抗体阳性率、GMT分别为:麻疹87.16%±3.14%、5.83±0.41(<1:8者56.90%);百日咳78.13%±9.19%、218.10±23.39(≥ 1:320者41.62%);DAT74.47%±11.04%、0.098±0.025;TAT75.86%±11.09%、0.136±0.03;脊灰(ELISA):I型89.99%、220.51,II型83.38%、201.27,III型86.09%、275.08,三个型79.48%、255.91(≥ 1;400者27.23%);乙脑(HI)67.47%±3.34%、39.44±1.48;OT试验阳性率24.73%。县市间、年龄组间差异显著(P<0.01)。4岁组调查接种率与免疫监测结果一致。麻疹抗体水平与发病呈完全负相关。基础免疫较好而加强免疫不够,甚至有免疫空白点、带。脊灰、麻疹、乙脑等的人群免疫屏障不够完善,有局部流行或爆发的可能。建议尽快进行5~14岁儿童的麻苗普种和5岁以下儿童的脊灰疫苗普服,加强村医培训,提高接种质量。

English Abstract:

A total of 1044 children selected in age groups of 4, 8 and 12 years old from 12 counties (cities) with stratified random sampling method were monitored on the present situation of immune levels according to the programme on immunization in 1991. The results showed that the positive rates and the geometric mean titers of antibodies to measles were 87.16%±3.14%, 5.83±0.41 (56.90%, <1:8), respectively; to pertussis were 78.13%±9.19% 218.10±23.39 (41.62%, ≥ 1:320); to DAT were 74.47%±11.04%, 0.098±0.025; to TAT were 75.86%±11.09%, 0.136±0.03; to poliomyelitis (ELISA) were type I 89.99%, 220.51, type II 83.38%, 201.27, type III 86.09%, 275.08, 3 types 79.48%, 255.91 (27.23%, ≥ 1:400); to Japanese B encephalitis (HI) were 67.47%±3.34%, 39.44 ±1.48. The conversion of OT was 24.73%. It showed signifioant difference among these counties and among 3 age groups (P<0.01). In 4-year age group, the vaccinated rate and the result of immune surveilance were the same. The antibody level and the incidence of measles showed negative correlation.

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