| 吴梓涛,干春兰,王爱霞.医院工作人员HBV-M的调查和接种乙肝疫苗的观察[J].Chinese journal of Epidemiology,1994,15(3):165-166 |
| 医院工作人员HBV-M的调查和接种乙肝疫苗的观察 |
| Investigation on HBV-Mamong Hospital Workers and Observation on the Efficacy of Vaccination against. Type B Hepatitis |
| Received:April 06, 1993 Revised:June 14, 1993 |
| DOI： |
| KeyWord: HBV-M 乙型肝炎疫苗 |
| English Key Word: HBV-M HBV vaccine |
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| Abstract: |
| 对我院院龄1~4年的315名工作人员进行HBV-M调查中,发现显性乙肝患者12例(3.8%)、隐性乙肝感染者126例(40%),共138例(43.8%)。其中HBsAg阳性20例(6.3%)、抗-HBc阳性27例(8.6%)、抗-HBs阳性91例(28.9%)。提示乙肝对医务人员健康有严重的威胁;但手术科室与非手术科室、血库、检验人员与其他科室人员的感染率无明显差异。对HBV-M均阴性的177例进行了血源性乙肝疫苗接种,注射第三针后,抗-HBs阳转158/173例(91.3%),认为我国血源乙肝疫苗使用安全且有良好的免疫效果。 |
| English Abstract: |
An epidemiological study on HBV infection among 315 staff of PUMC Hospital was carried out with detection of HBsAg, anti-HBs and anti-HBc by ELISA. The resulls showed that 138 persons had one or more markers of HBV infection and an overall HBV prevalence rate 43.8%. The positive rates of HBsAg anti-HBs, anti-HBc uere 6.3%, 28.9% and 8.6%, respectively. This indicates that HBV infection is a risk factor for medical staff, but there was no significant difference among medical, surgical and other members.
In 1992, 177 workers whose HBV markers were negative received 3 doses of HB vaccine at 0, 1 and 6 months, resnpectively. 91.3 percent of them showed an anti-HBs response one month after the last inoculation. The result shows that our national made HB vaccine is safe and immunogenic. |
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