| 高淑云,张景华,王文广,边立华,王杰,张经坤,曾光.血红蛋白筛查孕妇缺铁性贫血界限值的研究[J].Chinese journal of Epidemiology,1994,15(6):339-342 |
| 血红蛋白筛查孕妇缺铁性贫血界限值的研究 |
| A study on the Boundary Value of Hemoglobin Concentration for Screening Iron Deficiency Anemia in Pregnant Women |
| Received:January 17, 1994 |
| DOI： |
| KeyWord: 妊娠缺铁性贫血 筛查 约登指数 |
| English Key Word: Iron deficiency anemia in pregnancy Screening Youdon index |
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| Abstract: |
| 由于国内评价铁营养状况的检测方法尚未普及,目前一般只能依据血红蛋白(Hb)的检测结果来判断孕妇是否贫血和是否需要补铁。为了找出一合理的Hb界限值,以平衡由此带来的缺铁诊断的假阳性和假阴性偏性,笔者对258名孕妇的Hb、血清铁蛋白(SF)和红细胞原卟啉(FEP)三项指标检测的基础上,探讨了Hb的三个不同界限值(国内定界限值:Hb=100g/L;世界卫生组织定界限值;Hb=110g/L;和二者均值:Hb=105g/L)时,孕妇缺铁诊断假阳性和假阴性的程度,借用流行病学筛查的指标,提出了与SF和FEP检测结果相符合为标准,以两项约登指数(YI)之和最大为原则的衡量方法,以此选出Hb=105g/L为粗判孕妇缺铁性贫血的界限值为最佳。 |
| English Abstract: |
To evaluate whether a pregnant woman is in anemia or there exist the needs to replenish iron is usually based on the measurement of hemoglobin (HB) concentration, because the evaluation of iron nutritional status has not yet been used widely in our country.
Blood specimens were collected from 258 pregnant women, and concentrations of Hb, serum ferritin (SF) and free erythrocyte protoporphyrin (FEP) were determined to find out a reasonably boundary value of Hb concentration from the two different ones set by our country and WHO, respectively, and the one averaged the former two, i.e, 100g/L, 110g/L and 105g/L. False positivity and false negativity in diagnosis of iron deficiency anemia (IDA) for pregnant women were evaluated based on the measurement of SF and FEP concentrations as gold standards.Results showed that the optimal Hb concentration for preliminary diagnosis of IDA was 105g/L with maximizing Youdon index. |
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