| 王琪,徐桂珍,李家泰.临床分离286株革兰氏阴性菌耐药谱及R-质粒检测[J].Chinese journal of Epidemiology,1994,15(6):357-359 |
| 临床分离286株革兰氏阴性菌耐药谱及R-质粒检测 |
| Assay of R-Plasmid and Antibiotic Resistance Spectrum in 286 Strains of Gram-Negative Bacteria |
| Received:October 30, 1993 Revised:January 17, 1994 |
| DOI： |
| KeyWord: R-质粒 |
| English Key Word: R-plasmid |
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| Abstract: |
| 本文报道286株临床分离G-菌对10种抗菌素的药敏测定及R-质粒检测结果。实验发现目前主要流行的耐药菌为绿脓杆菌、大肠杆菌、克雷伯氏菌,耐药谱为Ap、Cb、Cm、Gm、Fb、CPV型,286株菌中272株对不同抗生素耐药(95.1%);178株菌为多重耐药菌(62.2%);53.3%的耐药菌携带R-质粒,13.3%的耐药标记为整传递,86.7%的耐药标记为部分传递。有意义的是来自不同时间、不同病房的病人分离菌却具有极相似的耐药谱及R-质粒传递谱,这些患者多为引流术及术后感染者。 |
| English Abstract: |
This paper reports the results of the sensitivity test to 10 antibiotics and the assay of R-plasmid on 286 strains of Gramnegative bacteria isolated from hospital. It was found that the main prevalent resistant bacteria are pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae. Their major antibiotic resistance spectrum is:Ampicillin, Cabenicillin, Chloramphemicol. Gentamicin, Furbenicillin.
The results showed that 272 of 288 strains resisted to 1-9 antibiotics (95.1%). One-hundred and seventy-eight of 286 strains resisted to more than 4 antibiotics (62.2%). One-hundred and fifty-one of 286 strains carried R-plamid in resistant bacteria (53.3%). 13.3% resistance markers were transferred with the whole R-factor. But 86.7& resistance markers were transferred with only a part of R-factor. |
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