我国部分脊髓灰质炎高发省急性弛缓性麻痹病例发病情况调查

王钊; 杨保平; 李慧芳; 张荣珍; 张振馨; 周军; 董胜利; 张健; 李全乐; 张兴录; 戴斐; 徐爱强; 陈小春; 楚金贵; Mac. Otten

Abstract

王钊,杨保平,李慧芳,张荣珍,张振馨,周军,董胜利,张健,李全乐,张兴录,戴斐,徐爱强,陈小春,楚金贵,Mac. Otten.我国部分脊髓灰质炎高发省急性弛缓性麻痹病例发病情况调查[J].Chinese journal of Epidemiology,1995,16(3):131-136

我国部分脊髓灰质炎高发省急性弛缓性麻痹病例发病情况调查

An Investigation on Acute Flaccid Paralysis (AFP) Cases in some Provinces with high Risk of Poliomyelitis of China

Received:December 10, 1994 Revised:January 17, 1995

DOI：

KeyWord: 急性弛缓性麻痹监测发病率

English Key Word: AFP Surveillance Prevalence

FundProject:

Author Name	Affiliation
Wang Zhao	The Department for Diseases Control of MOH, P. R. China
Yang Bao-Ping	The Department for Diseases Control of MOH, P. R. China
Li Hui-fang	The Department for Diseases Control of MOH, P. R. China
张荣珍	中国预防医学科学院
张振馨	协和医院
周军	The Department for Diseases Control of MOH, P. R. China
董胜利	The Department for Diseases Control of MOH, P. R. China
张健	中国预防医学科学院
李全乐	中国预防医学科学院
张兴录	中国预防医学科学院
戴斐	中国预防医学科学院
徐爱强	山东省卫生防疫站
陈小春	湖南省卫生防疫站
楚金贵	河北省卫生防疫站
Mac. Otten	WHO驻中国消灭脊灰技术顾问

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Abstract:

1994年6月中旬卫生部疾病控制司专业考察小组,在我国十个脊髓灰质炎(脊灰)高发省份随机抽取20个地区,对其45所地(市)级和13所县级医院进行了AFP病例的主动搜索,共查出1991~1994年5月发病的AFP病例681例,分布于101个县市。结果表明:0~14岁儿童AFP、脊灰、非脊灰AFP及GBS年平均发病率分别为1.04/10万、0.48/10万、0.57/10万及0.31/10万,其中脊灰发病率明显较1991年下降,其构成比由1991年的第一位逐年降低;此外,约95%的脊灰患者分布于0~4岁组,表明0~4岁儿童应为今后监测和保护的重点;非脊灰AFP发病率具有明显的地区性差异,认为采用"0~4岁非脊灰AFP发病率>1/10万"作为监测系统敏感性指标似更合乎国情。

English Abstract:

In the mid Jun, 1994, a study team organized by MOPH investigated AFP cases in 10 provinces with high prevalence of poliomyelitis (polio). Twenty prefectures and ten counties were selected randomly from each of 10 provinces and relevant prefectures. The team identified 681 AFP cases under 15 years old from 45 hospitals at prefecture level and 13 hospitals at county level based on hospital records from cases occurred during 1991-1994. AFP, Polio, Non-polio AFP and GBS (Guillian-Barre Syndrome) cases aged from 0-14 years scattered around 101 counties (cities) among target population and their average incidences by year were 1.04, 0.48, 0.57 and 0.31 (per 10⁵) respectively. Noticingly, the incidence of polio had reduced significantly since 1991, and its proportion among AFP was also reducing from first place yearly since 1991. In addition, over 95%of the polio cases were concentrated in the 4 year olds which indicated that the target population for surveillance and prevention should mainly be focusing on 0-4 year olds. As the incidence of non -polio AFP has been used as a current sensitive index of surveillance system, we noticed that the incidence rates had been significantly different from various regions. According to the analytic data, we recommend that "Rate of non-polio AFP in children 0-14 years of age greater than 1/10⁵" might be a better and more sensitive index for surveillance program in China.

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