| 江世平,黄全诚,陈俊民,吴才仰,李玉霜,徐志一,欧阳佩英.柳州市大规模人群甲型肝炎减毒活疫苗流行病学效果考核[J].Chinese journal of Epidemiology,1995,16(3):140-142 |
| 柳州市大规模人群甲型肝炎减毒活疫苗流行病学效果考核 |
| A Prospective Epidemiological Investigation on the Effect of China-mode Attenuated Live Vaccine Against Hepatitis A in the Population of Liu Zhou |
| Received:September 05, 1994 Revised:October 30, 1994 |
| DOI： |
| KeyWord: 甲肝减毒活疫苗 整群随机分组 |
| English Key Word: Hepatitis A attenuater live vaccine Random group sampling |
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| Abstract: |
| 应用国产甲型肝炎(下称甲肝)减毒活疫苗采用整群随机分组方法进行流行病学效果考核,经一年半时间观察,疫苗组发病率为15.91/10万(5/31 421),对照组为95.92/10万(30/31 277);而接种组中拒(漏)种的2 081人中,发病1例,发病率为48.05/10万,对照组误种760人中则无病例发生。外对照的714 461人中,发病644例,发病率为90.14/10万。外对照人群、对照组、接种组拒(漏)种人群发病率无明显差异。接种组发病率与以上三组人群发病率比较,保护率分别为82.35%、83.41%和66.89%,而与对照组的误种人群比较则无明显差别。 |
| English Abstract: |
| An 24-month prospective epidemiological investigation on the results of China-mode Hepatitis A attenuated live vaccine againist hepatitis A by random group sampling was carried out. The incidence of case group was 15.91/105 (5/31421), the incidence of control group was 95.92/105 (30/31277) which showed a signifecant difference. In case group 2081 persons who missed vaccination, there was one preson developed hepatitis A, making the incidence 48.05/105. In control group 760 persons were vaccinated by mistake and there was no case developed in this sub-population. There were 644 cases of hepatitis A in the external control group, the incidence was 90.14/105. Data showed that there was no significant difference among external control group, control group and persons from case group who missed vaccination. Comparing the data from case group and from the above 3 groups, the protective rates were 82.35%, 83.41% and 66.89%. respectively. When conparing the data from persons who had been mistakenly vaccinated in control group, there was no signifecant difference being noticed. |
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