| 张桂花,曹红谊,徐于信.围手术期应用抗生素降低医院感染效果的前瞻性研究[J].Chinese journal of Epidemiology,1995,16(3):160-163 |
| 围手术期应用抗生素降低医院感染效果的前瞻性研究 |
| A Prospective Study of Perioperative Antibiotic Prophylaxis in Reducing the rate of Nosocomial Infection Among Patients with Intracranial Tumors |
| Received:August 23, 1994 Revised:September 27, 1994 |
| DOI： |
| KeyWord: 医院感染 围手术期 抗生素 |
| English Key Word: Nosocomial infection Perioperative antibiotic prophylaxis Antibiotic |
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| Abstract: |
| 笔者研究了1992年7月至1993年6月期间住院的525名颅内肿瘤病人,采用前瞻性研究的方法,将病人随机分为实验组和对照组,其中实验组175人围手术期应用抗生素,发生医院感染11人(6.29%),对照组350人术后常规预防性应用抗生素,发生医院感染61人(17.43%),二者有显著性差别。在感染部位发病率方面,颅内感染发病率最高,其中实验组的颅内感染发病率为2.29%,对照组颅内感染发病率为8.00%,二者也有显著差别。另外,调查也提示围手术期应用抗生素降低了病人住院时间、住院期间应用抗生素的费用和使用抗生素的时间。 |
| English Abstract: |
| This paper analysed 525 intracranial neoplastic patients who were hospitalized from July, 1992 to June, 1993. The patients were randomly divided into control and experiment groups. In the experiment group, patients who received one kind of antibiotic during perioperation had a nosocomial infection rate of 6.29% (11/175), while the patients in the control group where antibiotics were routinely used as usual had a rate of 17.43% (61/350). There was a significant difference between the control (8.00%) and experiment group (2.29%) in terms of the intracranial infection incidence. Perioperative antibiotic prophylaxis showed great influence on the expenditure of antibiotics and duration of hospitalization in the patients with intracranial neoplastic tumors. |
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