| 谭爱军,何尚浦,黄铭西,李国光,龚兰英,郭有峰.膳食胡萝卜素对肺癌发病危险的影响[J].Chinese journal of Epidemiology,1995,16(4):199-202 |
| 膳食胡萝卜素对肺癌发病危险的影响 |
| A Matched Case-Control Study on the Relations between Beta-Carotene and Lung Cancer |
| Received:October 18, 1994 Revised:December 15, 1994 |
| DOI： |
| KeyWord: 肺肿瘤 胡萝卜素 |
| English Key Word: Lung neoplasms Carotene |
| FundProject: |
| Author Name | Affiliation | | Tan Ai-jun | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 | | He Shang-pu | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 | | Huang Ming-xi | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 | | 李国光 | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 | | 龚兰英 | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 | | 郭有峰 | Department of Epidemiology, Tongji Medical University, Wuhan, 430030 |
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| Abstract: |
| 通过156对1:1配比病例对照研究,分析了武汉地区肺癌患者及其一般疾病住院对照的膳食主要营养素摄入情况。结果表明,病例组膳食胡萝卜素、维生素C、纤维素摄入水平显著低于对照。作者还分析了膳食胡萝卜素摄入量与肺癌各病理类型发病危险的关系,按吸烟因素分层进行OR趋势检验,发现膳食胡萝卜素水平与肺腺癌病理类型的OR趋势无统计显著性差异,但与肺鳞癌及其它肺癌病理类型发病存在暴露剂量-反应关系。 |
| English Abstract: |
| In order to discover the relationship between dietary nutrients intake and risk of lung cancer 1:1 matched case-control study on 156 recent histologiclly diagnosed primary lung cancer patients and 156 patients with respiratory tumour and other related diseases as controls,was conducted in Wuhan. All cases and controls were asked to participate in the nutritional assessment program and a food frequency questionaire containing 64 food items was filled in. The findings showed that there was a statistically significant difference between dietary intake of beta-carotene between the two groups (2877.13±393.43 vs.3445±430.98μg/day). Having controled the confounding factor of cigarette smoking, a significant linear trend for lower dietary carotene intake toward higher lung cancer risk was observed. |
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