Abstract
侯安存,陈晶晶,金宗平,蒋秀高,胡淑德,张建中,李黎,赵惠芬.小儿幽门螺杆菌感染调查[J].Chinese journal of Epidemiology,1995,16(4):237-239
小儿幽门螺杆菌感染调查
An Epidemiological Survey on Helicobacter pylori Infection in Children
Received:December 19, 1994  Revised:April 03, 1995
DOI:
KeyWord: 幽门螺杆菌  尿素酶抗体
English Key Word: Helicobacter pylori  Anti-urease antibody
FundProject:
Author NameAffiliation
Hou An-cun Beijing Friendship Hospital, Beijing 100050 
Chen Jing-jing 中国预防医学科学院流行病学微生物学研究所 
Jin Zong-ping Beijing Friendship Hospital, Beijing 100050 
蒋秀高 中国预防医学科学院流行病学微生物学研究所 
胡淑德 Beijing Friendship Hospital, Beijing 100050 
张建中 中国预防医学科学院流行病学微生物学研究所 
李黎 Beijing Friendship Hospital, Beijing 100050 
赵惠芬 Beijing Friendship Hospital, Beijing 100050 
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Abstract:
      1993年6月~1994年6月期间,采用EL1SA检测血清中抗幽门螺杆菌尿素酶抗体,对394名小儿各年龄组自然人群感染率进行了调查。总体平均阳性率为15.7%,具有随年龄增加而增加的总趋势,至12岁组时阳性率达30%。其中1~3岁及7岁组阳性率相对较高,可能与家庭及学校内密切接触有关。此外,反复发生腹痛者其阳性率较无症状者明显增高(P<0.05)。
English Abstract:
      In this study serum anti-urease antibodies of Helicobacter pylori was examined in order to investigate the prevalence of H. pylori infection in 394 children between age 1 and 13. The results showed that the average infection rate was 15.7% with a tendency of increase infection rate with age, and by the age of 12 the H. pylori infection rate reached 30%, which was higher than those found in developed countries. We also noticed that there was a comparatively higher serapositivity among 1 and 7 year olds. This may possibly be due to the close contact between family members and school mates. In addition, the serum positive rate of antibody to H. pylori urease in children with recurrent abdominal pain was much higher than those asymptomatic children (P<0.05).
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