| 陈丽嘉,杨东亮,喻植群,李方和,汪由坤,郝连杰.血液病患者HBV和HCV感染现况调查[J].Chinese journal of Epidemiology,1996,17(2):74-76 |
| 血液病患者HBV和HCV感染现况调查 |
| A Prevalence Study on HBV and HCV Infection Status in Patients with Hemopathy |
| Received:February 20, 1995 Revised:March 25, 1995 |
| DOI： |
| KeyWord: 乙型肝炎病毒 丙型肝炎病毒 血液病 |
| English Key Word: HBV HCV Hemopathy |
| FundProject:本项研究为国家八五攻关项目 |
| Author Name | Affiliation | | Chen Li-jia | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 | | Yang Dong-liang | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 | | Yu Zhi-qun | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 | | 李方和 | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 | | 汪由坤 | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 | | 郝连杰 | Clinical Immunology Research Unit, Tongji Hospital of Tongji Medical University, Wuhan 430030 |
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| Abstract: |
| 对144例血液病患者HBV和HCV感染状况进行调查,HBsAg、抗-HBc和抗-HCV检出率分别为9.72%、36.81%及24.31%,而健康对照组分别为12.03%、46.30%和0.93%。HCV感染率与年龄、性别无关,但与受血史,受血次数密切相关。抗-HCV阳性者血清ALT水平明显高于抗-HCV阴性者,HBV/HCV重叠感染时ALT升高尤为明显。本组调查提示输血及应用血液制品是血液病患者感染HCV的重要途径。 |
| English Abstract: |
| A prevalence study on Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in 144 patients with hemopathy was carried out, using an enzyme linked immunosorbent assay (ELISA). The HBsAg, HBeAb and anti-HCV positive rates in sera of these patients were 9.72%, 36.81% and 24.31% respectively, comparing with data from healthy control subjects, 12.03%, 46.30% and 0.93% respectively. No correlation between HCV infection and patient's age or sex was noticed. Nevertheless the incidence of HCV infection was closely related to the history and the frequency of blood transfusion. The ALT level in sera of patients with HCV infection was higher than that of patients without HCV infection. The ALT level in sera was the highest in patients su perinfected with HBV and HCV. Our results suggested that blood transfusion and receiving blood products were important routes of HCV transmission in patients with hemopathy. |
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