| 唐时幸,孙德贵,陈万荣,赵秋敏,张华,张习坦.河北省固安县北斜村HCV感染者三年随访研究[J].Chinese journal of Epidemiology,1996,17(3):145-147 |
| 河北省固安县北斜村HCV感染者三年随访研究 |
| A Three-Year Follow-up Study of Hepatitis C Virus Infected Individuals from Beixie Village, Guan County, Hebei Province, China |
| Received:July 04, 1995 Revised:September 26, 1995 |
| DOI： |
| KeyWord: 丙型肝炎病毒 抗-HCV随访研究 |
| English Key Word: Hepatitis C virus Anti-HCV Follow-up study |
| FundProject: |
| Author Name | Affiliation | | Tang Shi-xing | Department of Epidemiology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071 | | Sun De-gui | 北京医科大学公共卫生学院 | | Chen Wan-rong | Department of Epidemiology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071 | | 赵秋敏 | Department of Epidemiology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071 | | 张华 | Department of Epidemiology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071 | | 张习坦 | Department of Epidemiology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071 |
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| Abstract: |
| 笔者对42例抗-HCV阳性者进行了三年随访研究,发现血清ALT异常者占18.1%~26.2%,HCV RNA阳性率为80%。三年间抗-HCV年阴转率仅0.95%,抗-HCV抗体几何平均滴度(GMT)160左右,1991年和1994年检测结果表明抗-HCV GMT值无显著差异,抗体滴度与血清ALT水平以及HCV RNA无关。 |
| English Abstract: |
| A total number of 42 anti-HCV positive individuals from Beixie village, Gu-an county, was followed for three years to study the dynamic change of alanine aminotransminase (ALT), anti-HCV titers as well as HCV RNA in serum. Research results showed that 18.1% to 26.2% of the individuals exhibited a rise in ALT values while the positive rate of HCV RNA was 80%. The yearly negative seroconversion rate of anti-HCV was only 0.95%. The geometric mean titer (GMT) of anti-HCV was around 160 and showed no significant difference between the paired serum samples collected in 1991 and in 1994. There were no statistical associations between the GMT value of anti-HCV and ALT level as well as HCV RNA in serum. |
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