程明亮,罗天永,潘念齐,冷祥康,黄堂珍.青年人中原发性肝癌致病因素探讨[J].Chinese journal of Epidemiology,1997,18(1):37-39 |
青年人中原发性肝癌致病因素探讨 |
A Study on the Multiple Factorial Causation of Hepatoma among Young Patients |
Received:March 19, 1996 Revised:April 22, 1996 |
DOI: |
KeyWord: 肝癌,原发性 乙型肝炎病毒 丙型肝炎病毒 |
English Key Word: Hepatocelluar carcinoma, Primary HBV HCV |
FundProject:本课题由贵州省项目基金部分资助 |
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Abstract: |
采用病例-对照研究方法,对50例青年人原发性肝癌与病人住地附近“健康者”进行流行病学调查和致病多因素探讨。比较乙肝病毒(HBV)、丙肝病毒(HCV)感染、饮酒等多因素作用的大小。单因素分析表明,HBV感染、肝癌家族史与青年人肝癌关系密切,OR值分别为25、3倍。提示HBV感染在青年人肝癌中的作用远远高于其他危险因素。 |
English Abstract: |
Pathogenetic significance of major risk factors to primary hepatoma among young people was investigated through a case-control study. The analysis of single-factor showed that there was close relationship between HBV infection, family history of hepatoma and the primary hepatocellular carcinoma among young people, with an OR 25.3. Multiple-factorial analysis indicated that the effect of HBV infection far exceeded other risk factors in the pathogenesis of primary hepatoma, suggesting that HBV infection might be a tnaor cause of primary hepatoma among young people. |
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