肝病患者检测血清可溶性白细胞介素2受体的意义

宣世英; 姜岭梅; 吕维红; 孙樱; 张健; 吴树华

Abstract

宣世英,姜岭梅,吕维红,孙樱,张健,吴树华.肝病患者检测血清可溶性白细胞介素2受体的意义[J].Chinese journal of Epidemiology,1997,18(2):92-94

肝病患者检测血清可溶性白细胞介素2受体的意义

The Significance of sIL-2R Detection in Various Hepatic Diseases

Received:August 28, 1996 Revised:September 27, 1996

DOI：

KeyWord: 可溶性白细胞介素2受体肝病

English Key Word: sIL-2R Hepatic disease

FundProject:

Author Name	Affiliation
Xuan Shi-ying	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011
Jiang Ling-mei	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011
Lu Wei-hong	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011
孙樱	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011
张健	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011
吴树华	Department of Infections Disease Qingdo Minicipol Hospital, Qingdao 266011

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Abstract:

为了揭示血清可溶性白细胞介素2受体（sIL-2R）在各类急慢性肝病的具体改变，并依其变化判断肝损害的程度。本研究采用单克隆与多克隆双抗体夹心酶联免疫吸附法测定了各类肝病的sIL-2R水平。结果示各组病例sIL-2R增高幅度不同，其中重症肝炎>急性肝炎>活动性肝硬化>慢性活动性肝炎>肝癌>代偿性肝硬化>慢性迁延性肝炎。结果提示，进行性肝损害病人的sIL-2R水平的变化可作为判定肝组织病变程度的指标之一。

English Abstract:

To study the alteration of the level of sIL-2R in acute and chronic hepatic diseases and its relation between alteration and the extent of damage to liver, the level of sIL-2R with hepatic disease was measured by a monoclonal and polyclonal Antibody ELISA. The result showed that the level increased differently in various hepatic diseases. The level of sIL-2R decreased when turning into severe hepatitis,acute hepatitis,active cirrhosis, chronic active hepatitis, hepatocarcinoma,compensative cirrhosis, chronic persistent hepatitis.It was suggested that the level of sIL-2R be considered of clinical value to estimate the extent of damage to liver in patients with progressive liver damage.

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