| 范若兰,郑素华,吴兆苏,曹丽华,凌颖.肺癌患者与发病前心理社会因素关系的病例对照研究[J].Chinese journal of Epidemiology,1997,18(5):289-292 |
| 肺癌患者与发病前心理社会因素关系的病例对照研究 |
| Study on the Relationship between Lung Cancer at Preclinic Stage and Psycho-social Factor-A Case-Control Study |
| Received:October 20, 1996 Revised:November 30, 1996 |
| DOI： |
| KeyWord: 肺癌 心理社会因素 比值比 对比研究 |
| English Key Word: Lung cancer Stage and psychosocial factor Odds ratio Comparative study |
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| Abstract: |
| 本文病例组为原发性肺癌309例（男193，女116），人群对照组1 231例（男768，女463）。在SINO-MONICA （WHO）项目的监测人群中进行病例对照研究，试图探索肺癌患者与发病前6项心理社会因素的关系。结果有3项与肺癌呈阳性关联。即情绪不能自我调节（OR=1.82，P<0.01），人际关系包括同事关系差（OR：1.37，P<0.05）、上下级关系差（OR=1.55，P<0.01）和精神长期受压抑（OR=4.14，P<0.01）。如将精神长期受压抑作为危险因素，按其人群暴露率8.8%计算，其人群归因危险度百分数（PAR%）为21.6%。 |
| English Abstract: |
| A case-control study of primary lung cancer patients including 309 case (male 193, female 116) and 1231 controls (male 768, female 463) was carried out in the monitored population for SINO-MONICA Project (WHO) during 1990-1993. This was a population based case-control study involved 0.75 million population in order to detect the relationship between lung cancer at preclinic stage and 6 psychosocial factors. There were 3 factors positively associated with lung cancer. They were 1) burst of "emotion and could not be controlled" (OR 1.82 P<0.01), 2) "poor working circumstances" including poor relationship with colleagues (OR 1.37 P<0.05) and superiors (OR 1.55 P<0.01) and the"depressive feeling for a long time" (OR 4.14 P<0.01). when we considered "long standing depressive feeling" as a risk factor for lung cancer and calculated by an exposure rate of 8.8%, the population attributable risk percent (PAR%) would be 21.6% (male 18.7%, female 26.4%). Our findings suggested that the relationship between lung cancer at preclinic stage and psycho-social factor did exist. |
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