福建省五型病毒性肝炎流行特征

李凌奋; 何家鑫; 赵莉莱; 周勇; 夏胜; 王枝新; 原寿基; 王成钦

Abstract

李凌奋,何家鑫,赵莉莱,周勇,夏胜,王枝新,原寿基,王成钦.福建省五型病毒性肝炎流行特征[J].Chinese journal of Epidemiology,1998,19(2):89-92

福建省五型病毒性肝炎流行特征

Epidemiologic Features of Viral Hepatitis in Fuj ian

Received:June 08, 1997 Revised:August 15, 1997

DOI：

KeyWord: 病毒性肝炎流行病学

English Key Word: Viral hepat itis Epidemio lo gy

FundProject:

Author Name	Affiliation
Li Lingfen	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
He Jiaxin	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
Zhao Lilai	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
周勇	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
夏胜	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
王枝新	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001
原寿基	福建省卫生厅
王成钦	Fujian Provincial Anti-Epidemic Station, Fuzhou 350001

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Abstract:

为了解福建省人群病毒性肝炎流行特征,福建省于 1992年进行五型病毒性肝炎感染的血清流行病学调查。采用多阶段分层整群随机抽样法,采集福建省疾病监测点自然人群的 12 37户家庭中 1～ 59岁居民血样本 380 9份。采用 RIA法检测 HBs Ag、抗 - HBs、抗 - HBc,采用 EIA法检测抗 - HAV、抗 - HCV、抗 - HDV、抗 - HEV和 HBe Ag。结果显示各标化流行率为 HAV 76.60 %、HBV77.2 6%、HCV 3.99%、HDV 2.10 %、HEV 18.80 %、HBs Ag 17.2 5%、抗 - HBs 34.33%、抗 - HBc68.58%、HBe Ag 8.4 2 %。农村 HAV、HBV、HEV流行率均高于城市。 HBs Ag流行率出现儿童峰和成人峰而且男性高于女性。 HBV和 HEV感染有明显的家庭聚集性。青壮年 HEV流行率高,城市儿童 HAV流行率低。提示福建省是 HAV、HBV、HCV、HEV的高流行区。预防甲、乙型肝炎病毒感染最有效策略是免疫接种甲、乙型肝炎疫苗。

English Abstract:

To study the prevalence and the epidemiologic features of viral hepatitis in Fujian, asero epidemiological survey on fivekinds of viral hepatit is infection has been car ried out in Fujian pro vince since 1992. Using stratified mulitist agerandom cluster sampling, 3809 serum sampleswere collected from 1237 families in g eneral population in the disease surveillance points in Fujian province. HBsAg, anti-HBs and anti-HBc were screened by RIA and HBeAg, anti-HAV, anti-HCVanti-HDV anti-HEV were by EIA. The results showed that the standardized prevalence rates of HAV, HBV, HCV, HDV, HEV, HBsAg, anti-HBs, anti-HBc and HBeAg wer e 76. 60%, 77. 26%,3. 99%, 2. 10%, 18. 80%, 17. 25%, 34. 33%, 68. 58% and 8. 42% respectively. The HAV, HBV,HEV prevalence rates in rural were higher than in urban a reas. The HBsAg prevalence rate among males was hig her than females, with peaks evidenced in 5-9 years old and 20-29 years old. T here seemed to be significant family clusterings of HBV and HEV infect ion. There was higher HEV prevalence rate among the youngr obusts but lower HAV prevalence rate among children in urban areas. These r esults sugg ested that Fujian is a highly pr evalent area for HAV, HBV, HCV and HEV infections. Thus HA and HB vaccinatio n should play as the most effective strategy in the prevention of HAV and HBV infections.

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