| 陈宪锐,玄梅香,吴多文,尹燕明,周玉霞,万宝美,魏佑农,付春生.庚型肝炎病毒感染研究[J].Chinese journal of Epidemiology,1999,20(2):85-87 |
| 庚型肝炎病毒感染研究 |
| Study on Hepatitis G Virus infection |
| Received:November 21, 1998 Revised:December 24, 1998 |
| DOI： |
| KeyWord: 庚型肝炎 庚型肝炎病毒 抗-庚型肝炎病毒 |
| English Key Word: Hepatitis G Hepatitis G virus Anti-HGV |
| FundProject:山东省教委资助 |
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| Abstract: |
| 目的了解山东省HGV感染状况,探讨HGV感染与HCV或HBV感染的关系。方法应用酶联免疫吸附试验（ELISA）对1082例病毒性肝炎患者、77例非甲至戊型肝炎患者和361名献血员进行了血清抗-HGV检测。结果共检出血清抗-HGV阳性者53例,阳性率3.49%.丙型肝炎患者血清抗-HGV阳性率（8.93%）显着高于乙型肝炎患者（3.32%）（χ2=8.80,P<0.01）.慢性肝炎患者血清抗-HGV阳性率（4.82%）显着高于急性肝炎患者（0.79%）（χ2=10.79,P<0.01）.重型肝炎患者血清抗-HGV阳性率（8.00%）显着高于急性肝炎患者（χ2=10.23,P<0.01）.结论HGV感染可表现为病毒携带状态、亚临床型和不同临床类型,丙型肝炎患者较乙型肝炎患者更易重叠感染HGV,HGV与HCV或HBV重叠感染可能与病情加重和慢性化的形成有关 |
| English Abstract: |
| ObjectiveTo find out the situation of HGV infection in Shandong Province,and to explore the relations between HGV infection and HCV or HBV infection.Methods Enzyme linked immunosorbent assay (ELISA)was used to determine the serum anti-HGV in 1082 patients with viral hepatitis, 77 patients with non A-E hepatitis and 361 blood donors.Results 53 patients whose serum anti-HGVs were positive (positive rate:3.49%)were noticed.The anti-HGV positive rate(8.93%)in patients with Hepatitis C was remarkably higher than that (3.32%)in patients with Hepatitis B(χ2 =8.80,P<0.01).The anti-HGV positive rate(4.82%)in patients with chronic hepatitis was significantly higher than that (0.79%)in patients with acute hepatitis (χ2 =10.79 ,P<0.01).The anti-HGV positive rate (8.00%)in patients with severe hepatitis was obviously higher than that in patients with acute hepatitis (χ2=10.23, P<0.01).ConclusionThe manifestations of HGV infection can be expressed as virus-carriers, subclinical infection or various clinical types.Patients w ith Hepatitis C were more subjective to be overlapped w ith HGV than the patients with Hepatitis B ;moreover, HCV or HBV infection superinfected with HGV is associated with exacerbation of patients' condition and the formation of chronic infection. |
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