| 庄勋,李立明.太仓农村地区女性胆囊结石危险因素病例对照研究[J].Chinese journal of Epidemiology,2000,21(1):44-47 |
| 太仓农村地区女性胆囊结石危险因素病例对照研究 |
| A case-control study of gallstone disease in female population in Taicang |
| Received:March 22, 1999 |
| DOI： |
| KeyWord: 胆囊结石 危险因素 病例对照研究 |
| English Key Word: Cholelithiasis Risk factor Case-control study |
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| Abstract: |
| 目的 概括太仓农村地区女性胆囊结石的危险因素。方法 选择5个村,对35～79岁的居民进行B超检查,共检出女性胆囊结石病例144例(其中现患病人105例,既往手术病人39例),选取女性随机人群对照371例,实施以人群为基础的病例对照研究。结果 年龄(OR=1.80)、胆石症家族史(OR=3.66)、高血压病史(OR=1.93)、饮用深井水(OR=0.54)、喜食肥肉(OR=1.77)、多孕次(OR=1.44)、绝经(OR=1.67)等因素与胆囊结石的OR值有显著性。结论 年龄、胆石症阳性家族史、高血压、喜食肥肉、多孕次、绝经与当地女性胆囊结石有关,饮用深井水有保护作用。 |
| English Abstract: |
| Objective To investigate the risk factors of gallstone disease in female population in Taicang. Methods A case-control study conducted on 144 cases and 371 controls aged 35-79 years in five villages. Diagnosis of gallstone disease was assessed by real-time ultrasonography. The case was considered as presence of gallstones at echograph and previous cholecytectomy. The controls were selected from a random sample of female participates. Results Through univariate and multivariate analysis,gallstone disease was significantly associated with age ( OR =1.80), family history of gallstone disease ( OR = 3.66), hypertension ( OR =1.93),fat intake ( OR =1.77), number of pregnancies ( OR =1.44) and menopause ( OR =1.67). Drinking water from deep well ( OR =0.54) was inversely associated with gallstone disease. Conclusion The main risk factors of female gallstone disease were age, family history of gallstone disease, fat intake,number of pregnancy and menopause. Drinking water from deep well was a protective factor of gallstone disease. |
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