| 何红,孙勇,周炳,全鲁端.高血压病患者血压变异与心脏结构和功能的关系[J].Chinese journal of Epidemiology,2001,22(4):296-299 |
| 高血压病患者血压变异与心脏结构和功能的关系 |
| The relationship of variability of blood pressure with cardiac structure and functions in hypertension |
| Received:August 20, 2000 |
| DOI： |
| KeyWord: 高血压 血管超负荷 左心室肥厚 |
| English Key Word: Hypertension Vascular overload Left ventricular hypertrophy |
| FundProject: |
| Author Name | Affiliation | | He Hong | Department of Cardiology, Affiliated Sir Run Run Shaw Hospital in Medical College, Zhejiang University, Hangzhou 310016, China | | Sun Yong | Department of Cardiology, Affiliated Sir Run Run Shaw Hospital in Medical College, Zhejiang University, Hangzhou 310016, China | | Zhou Bingquan | Department of Cardiology, Affiliated Sir Run Run Shaw Hospital in Medical College, Zhejiang University, Hangzhou 310016, China | | 全鲁端 | Department of Cardiology, Affiliated Sir Run Run Shaw Hospital in Medical College, Zhejiang University, Hangzhou 310016, China |
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| Abstract: |
| 目的研究原发性高血压病患者血压变异与心脏结构和功能的关系。方法 110例原发性高血压患者根据有无左心室肥厚被分为两组 ,比较两组血压负荷和血压变异的特征及对部分心脏结构和功能指标的影响。结果两组患者高血压年限差异无显著性 ,但左室重量 (LVM )、左室重量指数 (LVMI)、室间隔厚度 (IVS)、左室后壁厚度 (LVPW)和平均室壁厚度 (RWT)等均有显著不同。2 4h收缩压变异 (2 4hABPVs)、白昼收缩压变异 (dABPVs)、夜间收缩压下降率 (nSBPrr)、2 4h平均动脉压变异 (2 4hABPVm)、白昼平均动脉压变异 (dABPVm),高血压性血管超负荷指数(HINVOI)两组差异均有显著性①高血压病在早期已有心朋舒张功能的损害;②高血几性室肥厚不但与血管超负荷有关.并且与血少}、变异性有关;③因高血少}、知晓率低.高血少}、年限采川回忆法判断病情可靠性差;④年龄也是高血压性左室肥厚的一个危险因素 |
| English Abstract: |
| ObjectiveTo study the relationship of variability of blood pressure with cardiac structure and functions in essential hypertension.Methods A hundred and ten patients suffered from essential hypertension were divided into two groups according whether having left ventricular hypertrophy. The characteristics of overload and variability of blood pressure in both groups were analysed and several indexes on cardiac structure and function were compared between two groups. Results Both groups showed significant differences in the mass of left ventricle (LVM), the mass index (LVMI) of left ventricle, the thickness of interventricular septum (IVS), posterior wall of left ventricle (LVPW) and relative wall thickness (RWT) except for hypertensive ages. The ratio of E/A in both groups was significantly decreased. The rate of SBP load (SBPLO) both at day and night, the level of SBP in 24 hours and reductive rate of SBP at night (nSBPrr), the variabilities of systolic blood pressure (SBPV) and mean arterial pressure (MAPV) as well as hypertensive vascular overload index (HTNVOI) in two groups were obviously different. Conclusions 1) In early stage, the diastolic cardiac function in essential hypertension was damaged. 2) The happeness of left ventricular hypertrophy in essential hypertension was not only associated with the degrees and types of vascular overload, the increased variabilities of systolic blood pressure and mean arterial pressure, reversely with the reductive rate of SBP at night as well, but feebly with hypertensive age. 3) As a low awareness, hypertensive age was unreliable in the recollection. 4) Age was also a risk factor of left ventricular hypertrophy in essential hypertension. |
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