Abstract
应天翼,韩照中,苏国富.肠毒素性大肠杆菌疫苗的研制进展[J].Chinese journal of Epidemiology,2001,22(5):386-388
肠毒素性大肠杆菌疫苗的研制进展
Received:January 30, 2001  
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KeyWord: 戊型肝炎病毒  基因型  抗-HEV lgM抗体  抗-HEV IgG抗体
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Author NameAffiliation
应天翼 Second Division of Viral, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China 
韩照中 Second Division of Viral, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China 
苏国富 Second Division of Viral, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China 
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Abstract:
      细菌性腹泻是常见的肠道传染病,广泛流行于世界各地.据统计,全球年腹泻病人达30亿左右,我国年发病约8亿多人次,死亡率达0.02‰,其中最常见的是由肠毒索性大肠杆菌(Enterotoxigenicescherichiacoli,ETEC)引起的腹泻[1].由于是经口传播,所以常因食品或水源污染导致爆发性流行,特别是在自然灾害和战争时期更不易避免和控制,同时由于滥用抗菌药物而导致有耐药性细菌的大量增长,所以研制有效的疫苗加强免疫预防是迫切需要解决的公共卫生问题,但是目前还没有一种行之有效的ETEC疫苗[2-7].
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