Abstract
郭航远,何红,蒋峻,董梁,冯金燕,金娜,雷晶,朱艳.高血压病患者降压药物依从性研究[J].Chinese journal of Epidemiology,2001,22(6):418-420
高血压病患者降压药物依从性研究
Study on the compliance of antihypertensive durgs in patients with hypertension
Received:June 15, 2001  
DOI:
KeyWord: 高血压  依从性  药物
English Key Word: Hy pertension  Compliance  Drugs
FundProject:
Author NameAffiliation
GUO Hangyuan The Af filiated Sir Run R un Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
HE Hong The Af filiated Sir Run R un Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
JIANG Jun 310016 杭州, 浙江大学医学院附属邵逸夫医院心内科 
董梁 The Affiliated Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
冯金燕 The Affiliated Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
金娜 The Affiliated Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
雷晶 The Affiliated Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
朱艳 The Affiliated Sir Run Run Shaw Hospital of Zhejiang University, Hangzhou 310016, China 
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Abstract:
      目的 探讨高血压住院和门诊患者降压药物的依从性及其相关因素。方法 回顾性分析1995 年1 月至2001 年1 月高血压病住院患者816 例和门诊随访患者497 例的降压药物依从性及其相关因素:调查降压药物的使用情况和药物副作用的发生率:观察药物依从者和不依从者的血压水平变化。结果 高血压住院病人的心血管危险因素分层前几位依次为脂质代谢紊乱、吸烟、左室肥厚和糖尿病。出院后60.9 %的病人来院门诊随访,住院期间的药物依从率为63.4%,,出院时出院带药的依从率77.3 %,门诊随访期间的药物依从性为43.7%。药物不依从的原因包括:药物副作用、血压控制不佳、经济原因等。门诊随访过程中, 钙拮抗剂和利尿剂的副作用明显增加。药物依从者血压控制佳,波动小:而不依从者血压控制不佳,波动大。结论 出院后对出院带药的依从性最佳,住院期间的药物依从性次之,门诊随访期间的药物依从性最差
English Abstract:
      Objective To study the mpliance of antihypertensive durgs and its elated factors in inpatients and outpatients patients with hy ertension.Method Clinical data of 816 inpatients and 497 outpatients were review ed to study the compliance of antihy pertensive drug s and related factors as well as to investigate the utilization of anti-hypertensive medicament, the incidence of the side-effect of the medication and to ex plore the difference of the blood pressure control between the compliant group and the uncompliant g roup.Results The main risk factors of the hypertensive patients were in the order as:disorder of lipometabolism, smoking, left ventricular hypertrophy (LVH) and Diabetes mellitus.Six ty point nine percent of the inpatients were fo llowed up.The incidences of compliance were 63.4 % in the inpatients, 77.3% when being discharged, and 43.7 % in the outpatients.The cause of compliance w ere as follows:side-effect of the medication, failure to control BP, financial problems, etc.Data gathered during follow up period, it was found the side effect of the calcium antagonist and the diuretics inproved palpably.Those compliers controled their BP well, while little fluctuation of BP was observed.How ever, the uncompliers show ed different pictures, and the range of fluctuation of BP w as large.Conclusions The compliance of the medicament w as best among the outpatients to the discharge order, and the compliance of the outpatients was the w orst.
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