心理社会应激与综合健康效应的多组病例对照研究

李佳圆; 栾荣生; 薛朝润; 张游; 高家彦; 阳定宇; 罗小辉; 邓莉; 刘东磊

Abstract

李佳圆,栾荣生,薛朝润,张游,高家彦,阳定宇,罗小辉,邓莉,刘东磊.心理社会应激与综合健康效应的多组病例对照研究[J].Chinese journal of Epidemiology,2002,23(1):36-39

心理社会应激与综合健康效应的多组病例对照研究

A multi-team case-control study on the effects of psychosocial stress to overall health

Received:May 29, 2001

DOI：

KeyWord: 心理社会应激源综合健康效应病例对照研究

English Key Word: Psychosocial stressor Overall health effect Case-control study

FundProject:卫生部科学研究基金资助项目 ( 96 1 2 43)

Author Name	Affiliation
LI Jiayuan	Department of Epidemiology West China School of Public Health Sichuan University, Chengdu 610041
LUAN Rongsheng	Department of Epidemiology West China School of Public Health Sichuan University, Chengdu 610041
XUE Chaorun	四川省医学科学院附属医院
ZHANG You	四川省医学科学院附属医院
GAO Jiayan	四川省医学科学院附属医院
YANG Dingyu	简阳市卫生防疫站
LUO Xiaohui	简阳市卫生防疫站
DENG Li	Department of Epidemiology West China School of Public Health Sichuan University, Chengdu 610041
LIU Donglei	Department of Epidemiology West China School of Public Health Sichuan University, Chengdu 610041

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Abstract:

目的量化评价心理社会应激因素对人群健康不同损害程度的作用强度。方法以四川省简阳市三组人群978人(门诊病例177例,住院病例214例及健康对照587人)为研究对象,进行多组病例对照研究。分别收集一般人口学特征,用各量表测量心理社会应激因素及健康损害程度。进行秩和检验,方差分析,聚类分析,多类结果logistic回归模型拟和以及有序结果logistic回归模型拟和。结果有序结果logistic模型示,负性事件刺激量OR=1.335(P<0.01)。社会支持利用对健康损害程度有保护作用(OR=0.513)。结论负性生活事件刺激量是危害综合健康的主要因素,与健康的损害程度成剂量效应关系;社会支持利用是健康的维护因素。

English Abstract:

Objective To explore the quantitative relationship between the intensity of psychosocial stress and the degree of overall health damages. Methods A multi-group case-control study was designed and implemented. The cases included two groups of out-patients (177) and in-patients (214) in a hospital in Jianyang city, and controls (587) were from the follow-up cohort in the same city. Three groups were studied on the following contents: general demographic characteristics, psychosocial factors and the degree of health damages including mental, physical, and social status. Major statistical analyses were as follows: ranks test, ANOVA, cluster analysis, multinomial logistic regression and ordered-logit regression. Results Ordered-logit regression model showed that the odds ratio of negative life-events on degree of health damages was 1.335 (P 0.01). This result showed that there was a positive dose-effect relationship between the negative life-events score and overall health damages. The utility of social support to overall health had protective effect (OR= 0.513). Conclusion Negative life-events were the major risk factors to overall health, and there was a dose-effect relationship between negative events and health damages. Function of social support played a protective factor for health.

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