Abstract
胡永勤,干伟群,杨其法,范力强.一起乙型流行性感冒局部爆发性流行的调查[J].Chinese journal of Epidemiology,2002,23(2):130
一起乙型流行性感冒局部爆发性流行的调查
A follow up study on children conceived through intracytoplasmic sperm injection
Received:October 27, 2001  Revised:September 12, 2012
DOI:
KeyWord: 卵胞浆内单精子显微注射  围产期  多胎妊娠  出生缺陷
English Key Word: Intracytoplasmic sperm injection  Perinatal period  Multiple pregnancies  Birth defect
FundProject:国家重点基础研究发展计划(973计划)(2007CB948103);高等学校博士学科点专项科研基金(20050558097)
Author NameAffiliationE-mail
Yu Muxue Department of Pediatrics, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China zhoucanquan@hotmail.Com 
XU Yan-wen Reproductive Medical Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China  
ZHOU Can-quan Reproductive Medical Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China  
ZHUANG Si-qi Department of Pediatrics, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China  
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Abstract:
      2001年4月18日至5月8日,杭州市余杭区临平镇城北中学和中心小学发生一起乙型流行性感冒(流感)爆发.疫情发生后区疾病预防控制(疾控)中心等单位有关人员赶赴现场调查处理.现将调查情况报道如下.
English Abstract:
      Objective To investigate the perinatal complications, birth defects and growth of children conceived through intracytoplasmic sperm injection (ICSI). Methods A total of 575 children conceived by ICSI in our reproductive medical center, were studied. The follow up study would include items as pregnant complications, neonatal complications, birth defects in perinatal period, subsequently detected birth defects, body weight and body length/height growth. Results Prematurity and low birth weight of ICSI children were higher in the multiple births than in the singleton births. The rates of materal gestational hypertension, neonatal asphyxia, respiratory distress syndrome, infection diseases were higher in the multiple pregnancies than in the singleton pregnancies(P<0.05). Eleven ICSI children had died. Ten of them died in the neonatal period and they were preterm infants. One fullterm singleton ICSI child died of hepatoblastoma at the age of 2. The rate of birth defects in perinatal period was higher in ICSI children of multiple pregnancies than in the general population (P<0.05). The body weight and body length/height of most ICSI children had obtained the standard range between 1 to 3 year olds. Conclusion The higher rates of perinatal complications in ICSI children were closely related to multiple pregnancies.
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