| 么鸿雁,施侣元.中国人群肺癌发病危险因素的Meta分析[J].Chinese journal of Epidemiology,2003,24(1):45-49 |
| 中国人群肺癌发病危险因素的Meta分析 |
| Meta- analysis of the risk factors on lung cancer in Chinese people |
| Received:May 15, 2002 |
| DOI： |
| KeyWord: 肺肿瘤 Meta分析 危险因素 比值比 |
| English Key Word: Lung neoplasms Meta-analysis Risk factor Odds ratio |
| FundProject:卫生部慢性非传染性疾病预防与控制专题研究基金资助项目 ( 31) |
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| Abstract: |
| 目的: 探讨中国人群肺癌发生的主要危险因素, 为预防决策提供依据。方法: 利用Meta分析方法综合国内1990～2001年关于肺癌发病危险因素的研究文献41篇。累计病例5600例, 对照6892例。 结果: 各因素合并比值比分别为: 精神因素(3.34)、吸烟 (3.04)、室内煤烟污染(3.20)、室内油烟污染( 2.72 )、肺癌家族史 ( 2 .61)、饮食蔬菜摄入 ( 0.49)、水果摄入 ( 0.69)、体重指数( 1.57)、家族肿瘤史 ( 2.97)、呼吸系统疾病史 ( 2 .66)、厨房通风情况 ( 2.13 )、生活用煤 ( 1.50 )、被动吸烟 ( 1.42 )。结论: 目前影响中国人群肺癌发生的主要因素为精神因素、吸烟、室内环境污染、呼吸系统疾病史及家族史、蔬菜和水果摄入量等。 |
| English Abstract: |
| Objective: To provide evidence for decision-making on lung cancer prevention through studying the main risk factors related to the incidence of lung cancer in Chinese people. Methods: The results from 41 epidemiolo gical studies on risk factors of lung cancer from 1990 to 2001 were analyzed synthetically by Meta- analysis. The cumulative cases and controls were 5600 and 6892, respect ively. Results: The pools odds ratio (OR) values of mentality (3.34), smoking (3.04), indoor coal pollution (3.20), indoor cooking oil fume pollution (2.72), family history of lung cancer (2.61), vegetables (0.49), fruits (0.69 ), BMI (1.57), family history of other tumour (2.97), personal history of respiratory system diseases (2.66), ven ilation in kitchen (2.13), coal ever used in life (1.50), and exposure to environmental tobacco smoking ( 1.42). Conclusion: The main factors influencing the incidence of lung cancer in Chinese people were patients, mentality, smoking, indoor environmental pollution, personal history of respiratory system diseases, family history of cancer, intake of vegetables, fruits and so on. |
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