| 穆丽娜,周学富,丁保国,王如鸿,张作风,陈传炜,卫国荣,周晓明,姜庆五,俞顺章.饮绿茶降低吸烟、饮酒者消化系统癌发病的病例对照研究[J].Chinese journal of Epidemiology,2003,24(3):192-195 |
| 饮绿茶降低吸烟、饮酒者消化系统癌发病的病例对照研究 |
| A case-contral study on drinking green tea and decreasing risk of cancers in the alimentary canal among cigarette smokers and alcohol drinkers |
| Received:October 06, 2002 |
| DOI： |
| KeyWord: 绿茶 饮酒 吸烟 肿瘤 病例对照研究 |
| English Key Word: Green tea Alcohol drinking Smoking Cancer Case-control study |
| FundProject:国家自然科学基金资助项目(39730380);全国优秀博士学位论文作者专项基金资助项目(200157) |
| Author Name | Affiliation | | MU Lina | School of Public Health, Fudan University, Shanghai 200032, China | | ZHOU Xuefu | 江苏省泰兴市卫生防疫站 | | DING Baoguo | 江苏省泰兴市卫生防疫站 | | WANG Ruhong | 江苏省泰兴市卫生防疫站 | | ZHANG Zuofeng | UniversityofCalifornia, LosAngelesSchoolofPublicHealthLosAngeles, California, USA | | CHEN Chuanwei | School of Public Health, Fudan University, Shanghai 200032, China | | WEI Guorong | School of Public Health, Fudan University, Shanghai 200032, China | | ZHOU Xiaoming | School of Public Health, Fudan University, Shanghai 200032, China | | JIANG Qingwu | School of Public Health, Fudan University, Shanghai 200032, China | | YU Shunzhang | School of Public Health, Fudan University, Shanghai 200032, China |
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| Abstract: |
| 目的探讨饮绿茶是否可降低吸烟、饮酒者发生消化系统癌(胃癌、肝癌、食管癌)的危险度。方法在江苏省泰兴市进行以人群为基础的病例对照研究。结果病例为2000年泰兴市确诊的胃癌、肝癌、食管癌新病例且同意参加者,分别为206、204、218例。对照为随机选取的健康人群,在本地居住10年以上,并愿意参加者,共415人。结果显示:饮用绿茶可降低饮酒者患胃癌、肝癌、食管癌的危险度分别为81%、78%、39%,降低吸烟者患胃癌、肝癌、食管癌的危险度分别为16%、43%、31%。交互作用的检验显示饮绿茶可明显降低饮酒者患胃癌和肝癌的危险,交互项OR值分别为:0.23(95%CI:0.10～0.55)、0.25(95%CI:0.11～0.57)。结论饮绿茶对饮酒者患胃癌、肝癌的危险度具有降低作用,还可不同程度降低饮酒者患食管癌及吸烟者患胃癌、肝癌、食管癌的危险度。 |
| English Abstract: |
| Objective To explore the role of green tea in decreasing the risks of gastric cancer, liver cancer, esophageal cancer among alcohol drinkers or cigarette smokers. Methods A population based case-control study was conducted in Taixing, Jiangsu province. Results In Taixing city,identified cases of stomach, liver and esophageal cancers were chosen with informed consent. The numbers were 206, 204, 218 respectively. Controls were chosen from normal population having lived in the area for longer than 10 years, also with informed consent. Green tea drinking seemed to have decreased 81%, 78%, 39% risk for the development of gastric cancer, liver cancer and esophageal cancer among alcohol drinkers. It might also have decreased 16%, 43%, 31% on the risks of developing the three kinds of cancers among cigarette smokers. Interaction assessment showed that drinking green tea could significantly decrease the risk of gastric cancer and liver cancer among alcohol drinkers, with ORs of interaction item 0.23 (95%CI: 0.10- 0.55) and 0.25 (95%CI: 0.11- 0.57) respectively. Conclusion Habit of drinking green tea seemed to have significant protective effects on the development of both gastric and liver cancer among alcohol drinkers while, green tea also having some protective effect on esophageal cancer among alcohol drinkers and on three kinds of cancers among cigarette smokers. |
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