| 陈坤,俞维萍,朱益民.胃癌个体危险度及人群筛检数量化评价的研究[J].Chinese journal of Epidemiology,2003,24(4):310-313 |
| 胃癌个体危险度及人群筛检数量化评价的研究 |
| Gastric cancer risk of individual and population screening quantification evaluation research |
| Received:June 28, 2002 |
| DOI： |
| KeyWord: 胃肿瘤 筛检 数学模型 数量化评价 |
| English Key Word: Stomach cancer screening Mathematical model Quantification evaluation |
| FundProject:国家自然科学基金资助项目 ( 3 0 170 82 8) |
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| Abstract: |
| 目的 建立胃癌个体危险度判定及人群筛检的数量化模型。方法 在人群为基础的胃癌危险因素病例对照研究的基础上筛选出有统计学意义变量,应用概率论、模糊数学等原理和方法对胃癌危险因素和保护因素数量化,建立用于个体胃癌危险度测量和人群筛检的数量化评价方法 (数学模型)。采用两种不同的加权系数计算方法,分别确定该数量化方法的判别阈值为 0 .2 0和 0 .1 7,对 63例胃癌患者和 693名正常人进行实际判别。结果 灵敏度和特异度均分别达到 69%和 63 %左右,加权系数计算方法不同并不影响实际判别效果。b>结论 建立的胃癌个体危险度及人群筛检的数量化模型灵敏度和特异度尚理想 ;方法简便、易行、经济,有利于获得满意的受检率 ;可用于个体和群体 (社区 )的胃癌危险度测定 |
| English Abstract: |
| Purpose Aim to establish a risk of stomach cancer individual judgement and quantification model of population screening. Methods in gastric cancer risk factors of population-based case-control study on the basis of screening was statistically significant variables, probability theory and fuzzy mathematics theory and method of gastric cancer risk factors and protective factors of quantification, used to measure the individual risk of stomach cancer is established and the quantification of population screening evaluation method (mathematical model). Using two different weighted coefficient calculation method, respectively determine the quantification method of judging threshold of 0.20 and 0.20, 63 cases of gastric cancer patients and 693 normal people for actual discriminant. Results The results of sensitivity and speciality rate were 69% and 69% respectively, the weighted coefficient of different calculation method does not affect the actual effect of discriminant. Conclusion Conclusion established quantification model of gastric cancer risk of individual and population screening sensitivity and specific degree is ideal;Method is simple and easy, economic, and beneficial to obtain satisfactory client rate;Can be used for individual and group (community) in gastric cancer risk. |
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