| 吴磊,周跃平,钟宏京.赣南稀土矿区白血病病例对照研究[J].Chinese journal of Epidemiology,2003,24(10):879-882 |
| 赣南稀土矿区白血病病例对照研究 |
| A case-control study on the risk factors of leukemia in mining areas of rare-earth in South Jiangxi |
| Received:September 27, 2002 |
| DOI： |
| KeyWord: 白血病 稀土 危险因素 病例对照研究 |
| English Key Word: Leukemia Rare-earth Risk factors Case-control study |
| FundProject:国家自然科学基金重点资助项目(3986 90 03) |
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| Abstract: |
| 目的探索稀土环境污染与白血病的关系。方法采用1∶1配对的病例对照研究,于2001年11～12月在江西赣南稀土矿区选择经骨髓穿刺检查确诊的白血病患者51例,收集相关的资料进行条件logistic回归分析。结果多因素分析提示主要的危险因素是:经常饮用河水(OR=5.543)、住家距稀土矿距离及生活年限(OR=3.308)、有机磷农药接触史(OR=3.014);而经常饮茶(OR=0.164)提示为保护因素。结论稀土环境暴露史、有机磷农药接触史与当地白血病发病有关,而饮茶对白血病发生具有保护作用,但有待进一步研究 |
| English Abstract: |
| Objective I n order to explo re the correlation on radioactive co ntamina tio n of lanthanon to leukemia, and provide clues fo r the causes and prevention of leukemia in mining areas of rare-earth elements.Methods 1∶1 matched case-control study was used.A total of 51 clinically confirmed leukemia cases, individually matched with controls from general population, were inter viewed in mining areas of rareearth in South Jiang xi from November to December, 2001.Data were analyzed, using conditional logistic reg ression.Results The main risk factors would include frequently drinking water from river (OR =5.543), distance from residence to rare-earth mine and y ears for living in the area(OR =3.308), ex posure to organophosphorus pesticide (OR = 3.014).Tea drinking habit appeared to be a protective factor. Conclusions Leukemia seemed to be related to environmental pollution with rare-earth elements around theresidential areas and o rganophospho rus pesticide exposure.The protective factor o f tea drinking habit seemed to be unique in this study, which called for fur ther studies. |
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