| 翟凤英,张李伟,王春荣,段佳丽,曹若湘,王惠君,张坚.国际生命科学学会中国肥胖问题工作组推荐体重指数分类标准的血脂谱验证[J].Chinese journal of Epidemiology,2004,25(2):117-119 |
| 国际生命科学学会中国肥胖问题工作组推荐体重指数分类标准的血脂谱验证 |
| Validation of lipids on body mass index reference recommended by Obesity Working Group, International Life Science Association of China |
| Received:December 15, 2003 |
| DOI： |
| KeyWord: 肥胖 血脂 体重指数 儿童 青少年 |
| English Key Word: Obesity Lipids Body mass index Children Adolescents |
| FundProject:科技部科技基础性工作专项资金资助项目 |
| Author Name | Affiliation | | ZHAI Feng-ying | Institute of Nutrition and Food Safety, Chinese Center of Disease Control and Prevention, Beijing 100050, China | | ZHANG Li-wei | Institute of Nutrition and Food Safety, Chinese Center of Disease Control and Prevention, Beijing 100050, China | | WANG Chun-rong | Institute of Nutrition and Food Safety, Chinese Center of Disease Control and Prevention, Beijing 100050, China | | DUANJia-li | 北京市疾病预防控制中心学校卫生科 | | CAO Ruo-xiang | 北京市疾病预防控制中心学校卫生科 | | WANG Hui-jun | Institute of Nutrition and Food Safety, Chinese Center of Disease Control and Prevention, Beijing 100050, China | | ZHANG Jian | Institute of Nutrition and Food Safety, Chinese Center of Disease Control and Prevention, Beijing 100050, China |
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| Abstract: |
| 目的 探讨儿童青少年超重及肥胖与血脂谱的关系,验证国际生命科学学会中国肥胖问题工作组(WGOC)推荐的《中国儿童青少年超重和肥胖体重指数(BMI)值分类标准》。方法 随机抽取北京市6所中小学校2293名10～18岁健康中小学生作为观察对象,其中男生1124人,女生1169人,采取空腹血分离血清测定总胆固醇(TC)、总甘油三酯(TG)及高密度脂蛋白胆固醇(HDL-C),同时测量观察对象的身高及体重。结果 按照WGOC推荐的标准将人群分为BMI正常组(BMI<85百分位数)、超重组(BMI为85～95百分位数)及肥胖组(BMI≥95百分位数)。随着超重程度的增加,大多数男生及女生的TC及TG水平均呈现明显的增加趋势,HDL-C呈现降低趋势;且组间差异有极显著性(P<0.01)或显著性(P&<0.05),个别组间差异虽然没有显著性,但也是处在边缘水平。结论 研究中观察到多数年龄组BMI与血脂生化指标间存在着显著的剂量效应反应关系,说明WGOC推荐的BMI分类标准存在着一定的合理性,是早期预防中国成年期人群疾病的重要标准。 |
| English Abstract: |
| Objective To assess the relationship between overweight, obesity and blood lipid profiles of children and adolescents and to validate body mass index (BMI) cutoff points for overweight and obesity screening to Chinese children and adolcents, recommended by Working Group of Obesity, China (WGOC), International Life Science Association. Methods 2293 children and adolescents (1124 males and 1169 females), aged between 10 and 18 years, were randomly selected as samples from 6 schools in Beijing area. Fasting serum lipids including total cholesterol (TC), total triglycerides (TG), high density lipoprotein cholesterol (HDLC), thropometrical index as weight and height were measured. BMI equals to weight in kilograms were then divided by the square of height in meters. Results According to BMI cutoff points recommended by WGOC, samples fell into 3 groups including normal group (BMI 85 percentiles), overweight group (BMI≥85 and 95 percentiles) and obesity group (BMI≥ 95 percentiles). Results clearly showed an increase of both serum TC and TG and a decrease of HDLC when BMI was increasing, among most age group regardless of sex difference and the difference among BMI groups was statistically significant (P 0. 05 or P 0. 01). Conclusions Results of this study indicated that there was an obvious dose-effect relationship between BMI and lipid profiles which accounted for some rationality of the BMI cutoff points recommended by WGOC. The authors reckoned the findings important to managing relevant adult diseases during childhood, in China. |
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