Abstract
邵继红,沈洪兵,莫宝庆,徐耀初.社区人群高尿酸血症危险因素的病例对照研究[J].Chinese journal of Epidemiology,2004,25(8):688-690
社区人群高尿酸血症危险因素的病例对照研究
A community-based case-control study on risk factors of hyperuricemia among residents in the community
Received:August 21, 2003  
DOI:
KeyWord: 高尿酸血症  病例对照研究  危险因素
English Key Word: Hyperuricemia  Case-control study  Risk factor
FundProject:达能膳食营养研究与宣教基金(DIC2002-10)
Author NameAffiliation
Shao Jihong Department of General Physiology, Xuzhou Medical College, Xuzhou 221002, China 
Shen Hongbing Department of General Physiology, Xuzhou Medical College, Xuzhou 221002, China 
Mo Baoqing Department of General Physiology, Xuzhou Medical College, Xuzhou 221002, China 
Xu Yaochu Department of General Physiology, Xuzhou Medical College, Xuzhou 221002, China 
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Abstract:
      目的 探讨社区人群(20岁以上)高尿酸血症的危险因素.方法 采用病例对照研究方法,对研究对象进行单因素与多因素logistic回归分析.结果 经单因素筛选,有17个暴露因素与高尿酸有关;多因素分析,有5个因素在P=0.05水平被选入,高甘油三酯(OR=3.069)、饮酒(OR=2.032)、肥胖(OR=1.802)、口味偏辣(OR=1.877)、高血糖(OR=1.622)在模型中是高尿酸血症的独立危险因素.结论 高尿酸血症是一种与环境和生活方式有关的疾病,改变生活方式,如减少饮酒和合理饮食结构可能预防或减少高尿酸血症的发生,进而减少痛风的发生.
English Abstract:
      Objective To investigate the risk factors of hyperuricemia among residents aged≥20 years.Methods A community based case-clntrol study was conducted in 286 patients with 858 controls without hyperuricemia. Available data were analyzed by mono-factorial and multi-factorial logistic regression methods using SPSS 10.0 software.Results 17 factors related to exposure were identif-ied for hyperuricemia the mono-factorial analysis when;five factors were selected through multiple factoral logistic regression model at P=0.05 level.The risk factors on hyperuricemia were:hypertriglyceridemia (OR=3.069),alcohol consumption (OR=2.032),obesi ty (OR=1.802),taste of spicy food (OR=1.877) and hyperglycemia (OR=1.622).Conclusion Hyperuricemia is a di-sease associated with environment and style-life.Changing lifestyle,such as decreasing alcohol consumption and adorting proper structu-re of diet may prevent or decrease the chance of getting hyperuricemia anti gout.
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