诊断试验评价的Meta分析方法

刘云霞; 王洁贞; 庞春坤; 刘建平

Abstract

刘云霞,王洁贞,庞春坤,刘建平.诊断试验评价的Meta分析方法[J].Chinese journal of Epidemiology,2005,26(4):294-296

诊断试验评价的Meta分析方法

The use of Meta-analysis in the evaluation on diagnostic tests

Received:February 26, 2004

DOI：

KeyWord: Meta分析调整SROC法诊断试验

English Key Word: Meta-analysis Adjusted SROC method Diagnostic tests

FundProject:

Author Name	Affiliation
LIU Yun-xia	250033 济南,山东大学医学院第二医院山东大学循证医学研究所
WANG Jie-zhen	250033 济南,山东大学医学院第二医院山东大学循证医学研究所
PANG Chun-kun	山东省皮肤病性病防治研究所
LIU Jian-ping	International Health Research Group, Liverpool School of Tropical Medicine, UK

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Abstract:

目的介绍诊断试验评价的Meta分析方法。方法以7篇B超诊断脂肪肝的研究为例,运用调整SROC法对其进行综合评价。结果用调整SROC法求得B超的灵敏度为0.89(95%CI0.87～0.92),特异度为0.94(95%CI0.92～0.96),Q值为0.90。结果表明,B超的诊断价值较高,可作为脂肪肝诊断的有效方法。结论运用诊断试验评价的Meta分析方法,可对诊断试验的诊断价值做出综合评价,增加研究结论的统计功效,提高结论的可靠性。

English Abstract:

Objective To introduce Meta-analysis in evaluating diagnostic tests.Method Adjusted SROC method was used in assessing 7 diagnostic tests on fatty liver.Results The pooled sensitivity and specificity of type B ultrasonography were 0.89 [95% confidence interval(CI): 0.87- 0.92 ] and 0.94 (95%CI: 0.92- 0.96 ) respectively while the Q value was 0.90 by adjusted SROC method.The results indicated that the diagnostic value of type B ultrasonography were high,thus could be regarded as an effective method for fatty liver diagnosis.Conclusion Meta-analysis on evaluating diagnostic tests could be used to assess the diagnostic test to increase the power of conclusion,and to improveits its reliability.

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