| 张玫,汤哲,周英智,蔡玲,汤欣.北京地区老年人群幽门螺杆菌感染的血清流行病学研究[J].Chinese journal of Epidemiology,2005,26(9):687-689 |
| 北京地区老年人群幽门螺杆菌感染的血清流行病学研究 |
| Seroepidemiology study on helicobacter pylori (Cag A, Vac A) infection of elderly people in Beijing |
| Received:March 21, 2005 |
| DOI： |
| KeyWord: 螺杆菌,幽门 老年人群 感染 |
| English Key Word: HeUcdjacter pylori The elderly people Infectious |
| FundProject: |
| Author Name | Affiliation | | ZHANG Mei | Department of Gastroenterology, Xuanwu Hospital, Beijing 100053, China | | TANG Zhe | Department of Gastroenterology, Xuanwu Hospital, Beijing 100053, China | | ZHOU Ying-zhi | Department of Gastroenterology, Xuanwu Hospital, Beijing 100053, China | | CAI Ling | Department of Gastroenterology, Xuanwu Hospital, Beijing 100053, China | | TANG Xin | Department of Gastroenterology, Xuanwu Hospital, Beijing 100053, China |
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| Abstract: |
| 目的 评价北京地区老年人群幽门螺杆菌(Hp)及其亚型(CagA,VacA)感染的血清流行率及影响因素。方法 采用整群随机抽样的方法 人户问卷调查了北京不同地区(城区、郊区、山区) 60岁及以上的老年人2006名,应用免疫印迹法测定血清Hp CagA、VacA和Ureas抗体。结果 老年人群总的Hp感染率为83.4%,Ⅰ型Hp菌株感染率为56.0%;郊区和城区高于山区(P<0.001);以体力劳动为主的老年人Hp菌株的感染率高于以脑力劳动为主的老年人(P<0.05);以素食为主的老年人Ⅰ型Hp菌株感染率显著高于以高蛋白饮食为主的老年人(P<0.001)。结论 Hp在北京地区老年人群中存在着较高的血清流行率,以Ⅰ型Hp菌株感染为主,其亚型分布在年龄、地区和饮食习惯上存在显著差异。 |
| English Abstract: |
| Objective To assess the prevalence rate of Helicobacter pylori (H? pylori) in blood serum, its affecting factors and isoforms(CagA, VacA)infection in the elderly people in Beijing. Methods 2006 residents were investigated through household questionnaire in different areas of Beijing (urban, suburban and mountainous district),who were older than 60 years old. Serum H. pylori CagA, VacA and Ureas antibody was detected by immunoblotting. Results The total H. pylori infection rate was 83.4% and the infectious rate of I form pathogenic H. pylori was 56.0%. The incidence rate in urban or suburban district was higher than that of in mountainous district (P<0.001). I form H. pylori infection rate in people with heavy labor or young elderly were higher than that of intelegent work or older elderly (P<0.05). I form H. pylori infection rate in people of low diet was higher than that of high protein diet (P < 0.001). Conclusion The rate of H. pylori infection in blood serum was high among the elderly people in Beijing with most of it belonged to type I. However, significant differences were noticed on the distribution of isoforms in different age groups, areas,professions and diet habit. |
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