| 刘浩,朱立光,苏卫红,秦克江,庞明,陆健健,伍广伟,朱继金,陶新智,李醒三,曾知恒.广西壮族自治区40岁以上人群冠心病事件发病影响因素的队列研究[J].Chinese journal of Epidemiology,2005,26(12):964-966 |
| 广西壮族自治区40岁以上人群冠心病事件发病影响因素的队列研究 |
| Cox regression analysis on influencing factors of coronary heart disease among people over 40 years of age |
| Received:March 21, 2005 |
| DOI： |
| KeyWord: 冠心病事件 队列研究 影响因素 |
| English Key Word: Coronary heart disease events Cohort study Influencing factor |
| FundProject:广西壮族自治区卫生厅资助项目(9919;卫生部资助项目[1999(272)] |
| Author Name | Affiliation | | LIU Hao | 广西医科大学第一附属医院心内科, 南宁, 530027 | | ZHU Li-guang | 广西医科大学第一附属医院心内科, 南宁, 530027 | | SU Wei-hong | 广西壮族自治区江滨医院 | | QIN Ke-jiang | 广西壮族自治区卫生厅 | | PANG Ming | 广西壮族自治区江滨医院 | | LUJian-jian | 广西壮族自治区江滨医院 | | WU Guang-wei | | | ZHU Ji-jin | 广西医科大学第一附属医院心内科, 南宁, 530027 | | TAO Xin-zhi | 广西医科大学第一附属医院心内科, 南宁, 530027 | | LI Xing-nan | 广西医科大学第一附属医院心内科, 南宁, 530027 | | ZENG Zhi-heng | 广西医科大学第一附属医院心内科, 南宁, 530027 |
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| Abstract: |
| 目的探讨影响广西壮族自治区40岁以上人群冠心病事件发病的影响因素。在1991年全国高血压调查的基础上，对广西壮族自治区>40岁以上11818人进行了随访凋查，取得其冠心病发病资料。结果 冠心病事件的发生与收缩压(SBP)、舒张压(DBP)、脉压、吸烟、体重指数(BMI)和有无心肌梗死(心梗)史有关。Cox回归分析表明，有心梗史者较无心梗史者发生冠心病事件的相对危险度(RR)大21倍(95%CI：9．06～48．44)；脉压每增高10mm Hg(1mm Hg=0．133kPa)，冠心病事件发生的RR为1．29倍(95%CI：1．11～1．49)，大于DBP的1．18倍(95%CI：1．02～1．22)、SBP的1．13倍(95%CI：1．05～1．28)；吸烟者比不吸烟者的冠心病事件的RR增加1．23倍(95%CI：1．05～1．45)；每增加1的BMI，冠心病事件的RR增加1．03倍(95%CI：1．01～1．05)。结论 有心梗史者、高血压、吸烟、高BMI是冠心病发病的危险因素。 |
| English Abstract: |
| Objective To explore the affecting factors on coronary heart disease among people over 40 years of age in Guangxi area,China.Methods Baseline data was gathered through the Third National Blood Pressure Survey in 1991 in China.A total number of 11818 adults over 40 years old had been studied in Guangxi province.Data of morbidity and mortality of coronary heart disease was obtained.Results Cardiovascular events were related to systolic blood pressure, diastolic blood pressure, pulse pressure, smoking,BMI regardless of thier myocardial infarct(MI) history.Cox regression analysis showed that the relative risk for cardiovascular events increased by 21 [95% confidence intervaK (7): 9.06-48.44] times for those people having MI history.When pulse pressure, systolic blood pressure, diastolic blood pressure increased by every 10 mm Hg,the relative risk for cardiovascular events increased by 1.29(95% CI: 1.11-1.49),1.18(95% CI:1.02-1.22),1.13(95%CI: 1.05-1.28) respectively.There was 1.23(95%CI: 1.05-1.45) times higher in smoker than non-smoker on relative risk for cardiovascular events.When BMI increasing 1, the relative risk for cardiovascular events would increase 1.03(95% CI: 1.01-1.05) times.Conclusion Hypertension,smoking,increase of BMI were the risk faciors of coronary heart disease among people who were over 40 years of age. |
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