| 王玉林,秦鹏哲,刘于飞,吴新伟,柳洋,范建文,湛柳华,郭钜旋,陈小霜,蒋立云,周端华,狄飚,王鸣.广州市2006年禽流感患者未造成密切接触者传播的调查[J].Chinese journal of Epidemiology,2006,27(11):953-955 |
| 广州市2006年禽流感患者未造成密切接触者传播的调查 |
| Study on human case of avian influenza in Guangzhou 2006 without causing human-to-human transmission among close contacts |
| Received:August 15, 2006 |
| DOI： |
| KeyWord: 禽流感 密切接触者 流行病学调查 传播 |
| English Key Word: Avian influenza Close contacts Epidemiological investigation Transmission |
| FundProject: |
| Author Name | Affiliation | E-mail | | WANG Yu-lin | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | QIN Peng-zhe | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | LIU Yu-fei | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | WU Xin-wei | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | LIU Yang | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | FAN Jian-wen | 荔湾区疾病预防控制中心 | | | ZHAN Liu-hua | 越秀区疾病预防控制中心 | | | GUO Ju-xuan | 海珠区疾病预防控制中心 | | | CHEN Xiao-shuang | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | JIANG Li-yun | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | ZHOU Duan-hua | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | DI Biao | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | | | WANG Ming | Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China | wang-ming888@21cn.com |
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| Abstract: |
| 目的探讨人感染禽流感的密切接触者传播的可能性。方法根据卫生部公布的定义和办法,发现和确定密切接触者,开展流行病学调查和医学观察,并检测部分接触者的血清抗体。结果2006年广州市发生的禽流感患者,在发病前1个月未离开过该地,且无病、死禽的接触史；共发现了56名密切接触者,包括其女友、医务人员、亲属、朋友。经过7天的医学观察,未发现密切接触者被感染的现象。结论与SARS传播不同,广州市禽流感患者在潜伏期末和发病期间,未发现可能通过飞沫、唾液、黏膜、皮肤伤口直接接触等方式造成人间传播,提示目前禽流感病毒引起人间传播的能力不强。 |
| English Abstract: |
| Objective To explore the possibility of transmission from a human case of avian influenza to his close contacts.Methods Close contacts of the human case of avian influenza in Guangzhou 2006 were found out according to the definition and methods publicized by the Ministry of Health,People's Republic of China.Epidemiological investigation and medical observation were carried out.Serum antibodies were tested in some of the close contacts.Results The avian influenza patient had never left Guangzhou in the month prior to disease onset.No contact history with dead or diseased poultry was found. A total of 56 close contacts,including his girl friend,relatives,friends and medical staff who had taken care of him,were brought under medical observation for 7 days but none of them showed signs of infection, Conclusion Unlike SARS,direct contact with patient contracted with avian influenza at the end of incubation period and in the stage of illness through flying droplets,saliva,mucous membrane and skin injuries will not lead to human-to-human transmission,indicating the virus' ability to pass from human to human is limited. |
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