| 郭金玲,王宇明,梁淑英,王哲,胡晓燕,张亮.阻断艾滋病病毒母婴传播的成本效果分析[J].Chinese journal of Epidemiology,2007,28(3):258-261 |
| 阻断艾滋病病毒母婴传播的成本效果分析 |
| Study on the cost of preventing AIDS transmission from mothers to children：an effect analysis |
| Received:June 19, 2006 Revised:June 19, 2006 |
| DOI： |
| KeyWord: 艾滋病 母婴传播阻断 成本 效果 |
| English Key Word: AIDS Mother-child block Cost Effect |
| FundProject:国家科技攻关计划课题资助项目(2004BA719A13) |
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| Abstract: |
| 目的对艾滋病高发区某试点省的母婴HIv阻断措施进行经济学评价，探讨其成本效果和该措施的经济学效率。方法根据阻断人数和各项阻断措施的费用计算成本，计算避免l例感染HIv的费用，避免1个伤残(失能)调整生命年(DALY)损失的费用，阻断1例感染HIV的费用与1例感染Hlv后的经济损失对比.计算当成本与效果均等时的孕妇HIV阳性率。结果终止妊娠措施成本效果：每避免l DALY损失的费用平均为2264元；避免1例感染的费用平均46 963元，感染后平均每例经济损失为211 000元，效果成本比值为4.5：1。综合措施成本效果：避免1例感染成本为60 853元，避免l DALY损失的成本为2937元，效果成本比值为3.5：1。结论阻断HIV母婴传播的成本效果显著，当孕妇HIv阳性率>0.03%时进行筛查和母婴传播阻断均具成本效果价值，是对有限资源的有效利用。 |
| English Abstract: |
| Objective To evaIuate the costs of preventing AIDs transmission from motherS to children in a high—incidence area and to investigate relations between costs and effects，as well as to study the economical effects of this approach. Methods According to the number of patients and each strategy on prevention of AIDS transmiSsion，following aspects were calculated as：the cost of preventing each patient with HIV infection，to avoid the cost of one disability adjusted life year(DALY)，to evaluate the cost of each patient with either HIV infection or HIV—infected thereafter，and to calculate the HIV.positive rates in motherS at the same levels between costs and effects.ResuIts The∞sts—effects for stopping pregnancy：it was 2264 Yuan fOr preventing one DALY，the costs of avoi ding one case with HlV infection was 46 963 Yuan，but it was 21 1 000 Yuan frOm each patient after HIV infection，the ratio between effects and costs was 4.5：1. The coSts—effects for comprehensive strategies showed that the coSt was 60 853 Yuan for avoiding one case with HIV infection.It was 21 1 000 Yuan for each patient after HIV infection and the ratio between effects and costs was 3.5：1.Conclusion The cost—effect of preventing HIV tranSmiSsion from mothers to children was significant on the baSis of e∞n洲cal 1evel.It was rnore effective to evaluate the rdation between oosts and effects acoording to economical levd in screening and preventing transmission from rmtherS to children under the situation that the HIv-positive rate in pregnant mothers was Hlore than 0.03%. |
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