| 王文化,赵冬,刘飒,秦兰萍,吴兆苏.高血压对中老年人认知功能影响的研究[J].Chinese journal of Epidemiology,2007,28(6):532-535 |
| 高血压对中老年人认知功能影响的研究 |
| A cross-sectional study on cognitive function and innuencing factors patients with hypertension |
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| DOI： |
| KeyWord: 高血压 认知功能 影响因素 |
| English Key Word: Hypertension Cognitive function Influence factors |
| FundProject: |
| Author Name | Affiliation | | WANG Wen-hua | Beijing institute of Heart, Lung and Blod Vessel Disease, 100029, China | | ZHAO Dong | Beijing institute of Heart, Lung and Blod Vessel Disease, 100029, China | | LIU Sa | Beijing institute of Heart, Lung and Blod Vessel Disease, 100029, China | | Qin Lan-ping | Beijing institute of Heart, Lung and Blod Vessel Disease, 100029, China | | WU Zhao-su. | Beijing institute of Heart, Lung and Blod Vessel Disease, 100029, China |
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| Abstract: |
| 目的比较北京市城乡社区50～65岁中老年高血压患者和血压正常者之间的基本认知功能。方法2001年49月, 选择北京市城乡社区83例高血压患者以及83名年龄、性别、受教育水平和职业与患者1:1匹配的血压正常者为对照, 进行问卷调查、实验室检查和基本认知能力测验(包括数字鉴别、心算、汉字旋转、数字工作记忆、双字词再认、三位数再认和无意义图形再认)。对两组人群的基本认知能力进行比较, 并用多元逐步回归的方法分析影响认知功能的主要因素。结果高血压组基本认知能力的平均总分为63.62分, 低于对照组的68.58分(P<0.01);高血压组的平均反应时为1.25s, 慢于对照组1.17 s(P<0.05);高血压组的平均数字工作记忆广度为4.96, 低于对照组的5.63(P<0.05);高血压组双字词再认的平均成绩为12.05分, 低于对照组的13.45分(P<0.01);汉字旋转效率、三位数再认和无意义图形再认的成绩两组间的比较没有差异。多元逐步回归分析结果显示, 高血压是认知总成绩、平均反应时、工作记忆广度和双字词再认成绩的独立影响因素。结论中年和低龄老年高血压患者的知觉速度、工作记忆和字词记忆等基本认知能力明显比血压正常者差, 高血压可能是影响大脑基本认知功能的因素。 |
| English Abstract: |
| 0bjective To compare the differences of cognitive functions in patients with hypertension and normotensives, and to analyze the primary influencing factors on cognitive functions.Methods This was a cross-sectional study carried out in two community populations of Beijing in 2001.The study subjects consisted of 83 hypertensive individuals aged 50一65 years, who were both stroke and dementia-free, the control group was chosen with 83 normotensives who were matched one by one with hypertensive individuals on age, sex, educational level and occupation.Socio-demographic, behavioral, medical history, and physiological data were collected on all participants through interview and medical examination.A comprehensive and computerized neuropsychological battery was administered.Results The total score of Basic Cognitive Ability Examination on hypertension(63.62)was worse than that among controls(68.58)with PConclusion Patients with hypertension performed significantly worse than contr01s on velocity of perception, working memory and word memory.The findings suggested that the prevention of h)7pertensjon could protect cognitive function. |
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