北京市19 593名儿童青少年糖尿病患病现况调查

曹冰燕; 米杰; 巩纯秀; 程红; 颜纯; 侯冬青; 刘敏; 桑艳梅; 朱逞

Abstract

曹冰燕,米杰,巩纯秀,程红,颜纯,侯冬青,刘敏,桑艳梅,朱逞.北京市19 593名儿童青少年糖尿病患病现况调查[J].Chinese journal of Epidemiology,2007,28(7):631-634

北京市19 593名儿童青少年糖尿病患病现况调查

The prevalence of diabetes in children and adolescents of Beijing

Received:January 11, 2007 Revised:June 12, 2012

DOI：

KeyWord: 糖尿病患病率现况调查儿童青少年

English Key Word: Diabetes Prevalence Cross-sectional study Children and adolescents

FundProject:北京市科委基金资助项目(H030930030430,H030930030031);首都发展基金资助项目(2002-2005)

Author Name	Affiliation	E-mail
CAO Bing-yan	首都医科大学附属北京儿童医院, 北京 100045	chunxiugong@yahoo.com.cn
MI Jie	首都儿科研究所
GONG Chun-xiu	首都医科大学附属北京儿童医院, 北京 100045
CHENG Hong	首都儿科研究所
YAN Chun	首都医科大学附属北京儿童医院, 北京 100045
HOU Dong-qing	首都儿科研究所
LIU Min	首都医科大学附属北京儿童医院, 北京 100045
SANG Yan-mei	首都医科大学附属北京儿童医院, 北京 100045
ZHU Cheng	首都医科大学附属北京儿童医院, 北京 100045

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Abstract:

目的了解北京市儿童青少年糖尿病(DM)患病的流行特征并分析其在地区、性别和年龄的分布差异.方法以2004年3-10月北京地区6～18岁学龄儿童为研究对象,采用随机整群抽样方法抽取了北京市城乡7个区(县)19 593名在校中小学生,用空腹指末梢血糖进行DM筛查,根据1999年WHO的诊断标准进行DM(DM:空腹毛细血管全血血糖≥6.1 mmol/L)和空腹血糖受损(IFG:空腹毛细血管全血血糖≥5.6 mmol/L并<6.1 mmol/L)的诊断.结果总体DM和IFG年龄标化患病率分别为5.7‰和13.5‰,男性明显高于女性(7.7‰、3.6‰).DM、IFG年龄标化患病率东城区最高,伴高肥胖率;而平谷县最低(8.9‰和27.4‰,2.0‰和7.5‰).各区域之间DM患病率男、女性无明显差异,但男性IFG患病率东城区最高(P<0.0001).总体DM患病率随年龄增长而增高;IFG患病率以10～14岁年龄组最高.男性DM和IFG发生率最高年龄组分别为15～18岁和10～14岁,女性均为10～14岁.结论北京市6～18岁儿童青少年DM及IFG存在较高流行率.

English Abstract:

Objective To study the prevalence of Diabetes mellitus (DM) in children and adolescents and to describe the characteristics on age,gender and district distribution of schoolchildren,in Beijing.Methods A cross-sectional screening program the fasting capillary blood glucose(FCBG)was carried out in 19 593 schoolchildren in 7 areas of Beijing from March to October,2004.According to the WHO diagnostic criteria:DM was set as FCBG≥6.1 mmol/L,impaired fasting glucose (IFG) was set as 5.6 mmol/L≤FCBG6.1 mmol/L.Results The total aggregate age-adjusted prevalence rates of DM and IFG were 5.7‰and 13.5‰,respectively.The prevalence rates of DM and IFG in males were significantly higher than that in females (7.7‰vs.3.6‰and 26.8‰vs.11.3‰.DMχ²=12.27,P=0.0005;IFGχ²=47.29,P=0.0000).Among seven districts,East District had the highest prevalence rates of DM and IFG,8.9‰and 27.4‰(companied high obesity 28.68%) while Ping-Gu District having the lowest ones as2.0‰and 7.5‰(obese 12.75%) respectively (χ²=13.75,andχ²=32.65,P=0.0002 and P0.0001).The DM prevalence rates between districts ranged from 2.0‰to 8.9‰,χ²=18.94,P=0.004 and the IFG prevalence of districts ranged from 7.5‰to 27.4‰(χ²=52.05,P0.0001).The prevalence rates of DM among different age groups increased with age,with the highest prevalence of IFG on the 10-14 age group.Among boys,the highest prevalence rates of DM and IFG fell in the 15-18 and 10- 14 age groups respectively while the highest prevalence rates on both DM and IFG among girls were in the same age group 10-14.Conclusion The high prevalence rates on DM and IFG were seen in Beijing and showed significant discrimination on age,gender and district distribution.More developed urban district and males had a higher prevalence,companied by higher obesity prevalence.Age seemed to be a high risk factor on DM for boys while the puberty development seemed a high risk factor for girls.

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