河南省2000-2005年人狂犬病流行特征与病原学分析

郝宗宇; 张永振; 孙建伟; 熊成龙; 张彦平; 王海峰; 张爱梅; 李林红

Abstract

郝宗宇,张永振,孙建伟,熊成龙,张彦平,王海峰,张爱梅,李林红.河南省2000-2005年人狂犬病流行特征与病原学分析[J].Chinese journal of Epidemiology,2007,28(7):720

河南省2000-2005年人狂犬病流行特征与病原学分析

Analysis of pathogene and epidemical characteristics of human rabies in Henan province from 2000 to 2005

Received:December 06, 2006

DOI：

KeyWord: 狂犬病狂犬病毒流行特征

English Key Word: Rabies Rabies virus Epidemical characteristic

FundProject:广西自然科学基金资助项目(9912026)

Author Name	Affiliation
HAO Zong-yu	河南省疾病预防控制中心, 郑州 450016
ZHANG Yong-zhen	中国疾病预防控制中心传染病预防控制所
SUN Jian-wei	河南省疾病预防控制中心, 郑州 450016
XIONG Cheng-long	中国疾病预防控制中心传染病预防控制所
ZHANG Yan-ping	河南省疾病预防控制中心, 郑州 450016
WANG Hai-feng	河南省疾病预防控制中心, 郑州 450016
ZHANG Ai-mei	河南省疾病预防控制中心, 郑州 450016
LI Lin-hong	河南省疾病预防控制中心, 郑州 450016

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Abstract:

为了解河南省2000-2005年人狂犬病流行情况和病原学特征,进行回顾性调查,并对2005年采集的犬脑组织做病原分子生物学及遗传学分析.

English Abstract:

Objective To investigate the possible risk factors of congenital malformations in cities of Guangxi.Methods A case-control study was carried out on 281 cases of congenital malformations and 730 controls. Analysis of simple factor and multiple factors unconditional logistic regression were done.Results The analysis of simple factor and multiple factors showed that main risk factors of congenital malformations as multiple pregnancies (OR=2.6), pregnancy complications (OR=3.2), exposure to chemical substances before or during pregnancy (OR=3.0), taking sedatives (OR=10.2), hormone drug (OR=9.4) or Chinese herbal medicines (OR=2.5) during the early stage of pregnancy, mothers' blood type as AB (OR=3.5) or A (OR=2.2), mothers' emotion being nervous and melancholy (OR=2.6), mothers' occupation being workers (OR=3.8) or peasants (OR=3.0), fathers' exposure to noise (OR=5.7) or suffering from chronic diseases (OR=2.8).Conclusions Some risk factors were identified as having important effect on perinatal congenital malformations, including taking sedatives, hormone drug or Chinese herbal medicines during the early stage of pregnancy, mothers' emotion being nervous and melancholy,multiple pregnancies, pregnancy complications, exposure to chemical substances before or during pregnancies,mothers' blood type as AB or A, mothers' occupation being workers or peasants, fathers' exposure to noise or suffering from chronic diseases.

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